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Showing 1–3 of 3 results

Advanced filters: Author: Jonathan G. Van Vranken Clear advanced filters

A proteome-wide atlas of drug mechanism of action

A proteome-wide atlas of the effect of 875 compounds reveals mechanisms of action and off-target effects.

Dylan C. Mitchell
Miljan Kuljanin
Steven P. Gygi
Research02 Jan 2023
Nature Biotechnology

Volume: 41, P: 845-857
TMTpro reagents: a set of isobaric labeling mass tags enables simultaneous proteome-wide measurements across 16 samples

A set of isobaric labeling reagents called TMTpro enables deep quantitative comparisons of proteome measurements across 16 samples.

Jiaming Li
Jonathan G. Van Vranken
Joao A. Paulo
Research16 Mar 2020
Nature Methods

Volume: 17, P: 399-404
Vms1p is a release factor for the ribosome-associated quality control complex

The ribosome-associated quality control complex (RQC) functions to disassemble stalled ribosomes. Here the authors find that the tRNA hydrolase Vms1 is involved in the release of nascent peptide from stalled ribosomes.

Olga Zurita Rendón
Eric K. Fredrickson
Jared Rutter
ResearchOpen Access06 Jun 2018
Nature Communications

Volume: 9, P: 1-9