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Showing 351–372 of 372 results

Advanced filters: Author: Jonathan M Gibson Clear advanced filters

Structural determinants of CO₂-sensitivity in the β connexin family suggested by evolutionary analysis

Valentin-Mihai Dospinescu et al. present an evolutionary analysis of the connexin Cx26, by comparing the structure and function of this protein in fish, Xenopus and reptiles. They find that Cx26 acts as a CO₂ sensor in mammals and reptiles, but not fish or amphibia, and loss of its C-terminal tail is linked to this gain of function.

Valentin-Mihai Dospinescu
Sarbjit Nijjar
Nicholas Dale
ResearchOpen Access04 Sept 2019
Communications Biology

Volume: 2, P: 1-14
Finding the missing heritability of complex diseases

Teri A. Manolio
Francis S. Collins
Peter M. Visscher
Reviews08 Oct 2009
Nature

Volume: 461, P: 747-753
Do antibiotics prior to dental extractions reduce adverse post-operative outcomes?

Darshini Ramasubbu
Jonathan Lewney
Comments & Opinion17 Dec 2024
Evidence-Based Dentistry

Volume: 26, P: 46-47
Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2

Evan Bolyen
Jai Ram Rideout
J. Gregory Caporaso
Correspondence24 Jul 2019
Nature Biotechnology

Volume: 37, P: 852-857
Dual direction CRISPR transcriptional regulation screening uncovers gene networks driving drug resistance

Carlos le Sage
Steffen Lawo
Benedict C. S. Cross
ResearchOpen Access18 Dec 2017
Scientific Reports

Volume: 7, P: 1-10
Correction to: Solve-RD: systematic pan-European data sharing and collaborative analysis to solve rare diseases

Birte Zurek
Kornelia Ellwanger
Andreas Rump
Amendments and Corrections13 Aug 2021
European Journal of Human Genetics

Volume: 29, P: 1459-1461
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

The UK IBD Genetics Consortium and the Wellcome Trust Case Control Consortium 2 report results of a genome-wide association study of ulcerative colitis. They identify three new loci associated with the disease, including the HNF4A region on 20q13.

Jeffrey C Barrett
James C Lee
David P Strachan
Research15 Nov 2009
Nature Genetics

Volume: 41, P: 1330-1334
Novel high throughput pooled shRNA screening identifies NQO1 as a potential drug target for host directed therapy for tuberculosis

Qing Li
Ahmad F. Karim
Roxana E. Rojas
ResearchOpen Access14 Jun 2016
Scientific Reports

Volume: 6, P: 1-18
Reduced Energy Expenditure in Preobese Children Treated for Acute Lymphoblastic Leukemia

John J Reilly
Jonathan C Ventham
Brenda Gibson
Research01 Oct 1998
Pediatric Research

Volume: 44, P: 557-562
A dataset of Antarctic ecosystems in ice-free lands: classification, descriptions, and maps

Anikó B. Tóth
Aleks Terauds
David A. Keith
ResearchOpen Access22 Jan 2025
Scientific Data

Volume: 12, P: 1-16
Risk factors mediating the effect of body mass index and waist-to-hip ratio on cardiovascular outcomes: Mendelian randomization analysis

Dipender Gill
Verena Zuber
Paul Elliott
ResearchOpen Access17 May 2021
International Journal of Obesity

Volume: 45, P: 1428-1438
Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP

Eleanor M. Wigmore
Jonathan D. Hafferty
Andrew M. McIntosh
ResearchOpen Access31 Jan 2019
The Pharmacogenomics Journal

Volume: 20, P: 329-341
ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

Ali Abbas
Sheryl Ann Abdukahil
Luis Felipe Reyes
ResearchOpen Access30 Jul 2022
Scientific Data

Volume: 9, P: 1-22
Author Correction: Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

Joana Carlevaro-Fita
Andrés Lanzós
Christian von Mering
Amendments and CorrectionsOpen Access08 Dec 2022
Communications Biology

Volume: 5, P: 1
Potential roles of sex-linked differences in obesity and cancer immunotherapy: revisiting the obesity paradox

Logan V. Vick
Spencer Rosario
William J. Murphy
ReviewsOpen Access23 May 2024
npj Metabolic Health and Disease

Volume: 2, P: 1-12
Mechanical stretch and shear flow induced reorganization and recruitment of fibronectin in fibroblasts

Robert L. Steward
Chao-Min Cheng
Philip R. LeDuc
ResearchOpen Access08 Nov 2011
Scientific Reports

Volume: 1, P: 1-12
Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error

Qiao Fan et al. report a genome-wide association analysis of corneal curvature—an important measurement for identifying vision problems, such as myopia—in more than 45,000 individuals of either European or Asian ancestry. They identify 47 loci, 26 of which are novel, with some showing population-specific effects and pleiotropic effects on eye elongation and myopia.

Qiao Fan
Alfred Pozarickij
Ching-Yu Cheng
ResearchOpen Access19 Mar 2020
Communications Biology

Volume: 3, P: 1-14
Multi-trait genome-wide association study identifies new loci associated with optic disc parameters

The International Glaucoma Genetics Consortium reports a genome-wide association study meta-analysis of optic disc parameters relevant to primary open-angle glaucoma. They identify two novel variants in PPP1R36-PLEKHG3 and SERPINE3 by multi-trait analysis in European-ancestry cohorts that were replicated in independent Asian cohorts.

Pieter W. M. Bonnemaijer
Elisabeth M. van Leeuwen
Cornelia M. van Duijn
ResearchOpen Access27 Nov 2019
Communications Biology

Volume: 2, P: 1-12
The United States COVID-19 Forecast Hub dataset

Estee Y. Cramer
Yuxin Huang
Nicholas G. Reich
ResearchOpen Access01 Aug 2022
Scientific Data

Volume: 9, P: 1-15
Reproducibility of the NEPTUNE descriptor-based scoring system on whole-slide images and histologic and ultrastructural digital images

Laura Barisoni
Jonathan P Troost
Stephen M Hewitt
Research22 Apr 2016
Modern Pathology

Volume: 29, P: 671-684
Solving unsolved rare neurological diseases—a Solve-RD viewpoint

Rebecca Schüle
Dagmar Timmann
Andreas Rump
ReviewsOpen Access10 May 2021
European Journal of Human Genetics

Volume: 29, P: 1332-1336
Solve-RD: systematic pan-European data sharing and collaborative analysis to solve rare diseases

Birte Zurek
Kornelia Ellwanger
Andreas Rump
ReviewsOpen Access01 Jun 2021
European Journal of Human Genetics

Volume: 29, P: 1325-1331

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