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Showing 1–6 of 6 results
Advanced filters: Author: Jongcheol Seo Clear advanced filters

  • The ribosome has evolved to link standard amino acids into proteins via peptide bonds. Here, authors expand its chemistry to directly synthesize novel 5- and 6- membered cyclic backbones from noncanonical monomers, revealing new ribosomal potential for advanced biopolymer design.

    • Kanghun Lee
    • Hyeongwoo Park
    • Joongoo Lee
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-14

  • There is increasing evidence that highly dynamic, polydisperse peptide oligomers are the toxic species in amyloid-related diseases such as Alzheimer's and Parkinson's. Now, the secondary structure of individual amyloid oligomers has been analysed directly for the first time using a combination of ion-mobility spectrometry–mass spectrometry and gas-phase infrared spectroscopy.

    • Jongcheol Seo
    • Waldemar Hoffmann
    • Kevin Pagel
    Research
    Nature Chemistry
    Volume: 9, P: 39-44

  • Phoenix Fluor 555 (PF555) is a bright dye with an exceptional, order-of-magnitude longer photobleaching lifetime than conventional organic dyes that enables extended live-cell single-molecule imaging without anti-photobleaching additives.

    • Do-Hyeon Kim
    • Hong Minh Triet
    • Sung Ho Ryu
    Research
    Nature Methods
    Volume: 22, P: 550-558

  • The engineering of metabolite secretion from microorganisms can lead to many applications in synthetic biology. In this article, the authors engineer a metabolite trafficking system for the secretion of medicinal terpenes.

    • So-Hee Son
    • Jae-Eung Kim
    • Ju Young Lee
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-9

  • Octameric complexes of serine are long known for their special properties, such as their enhanced stability and preference for homochirality. Yet, there is no consensus on their structures. Now, experimental data on the serine octamer–dichloride complex is presented that supports a highly symmetrical, highly stable structure.

    • Jongcheol Seo
    • Stephan Warnke
    • Gert von Helden
    Research
    Nature Chemistry
    Volume: 9, P: 1263-1268