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Showing 1–5 of 5 results
Advanced filters: Author: Jordan W. Raff Clear advanced filters

  • Centrosomes are important microtubule organizers. As many proteins are concentrated at centrosomes, including cell cycle and signalling regulators, centrosomes are also likely to coordinate important cell decisions. Recent findings have shed light on the functions of centrosomes in animal cells and on the mechanisms of centrosome assembly and maturation during mitosis.

    • Paul T. Conduit
    • Alan Wainman
    • Jordan W. Raff
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 16, P: 611-624

  • Centrioles are among the most beautiful of biological structures. How their highly conserved nine-fold symmetry is generated is a question that has intrigued cell biologists for decades. Two recent structural studies provide the tantalizing suggestion that the self-organizing properties of the SAS-6 protein hold the answer.

    • Matthew A Cottee
    • Jordan W Raff
    • Hélio Roque
    Comments & Opinion
    Nature Chemical Biology
    Volume: 7, P: 650-653

  • Early fruitfly embryos have an unusual means of halting the division of any nuclei containing damaged DNA. A key component of this mechanism has now been identified, and might have implications for cancer.

    • Jordan W. Raff
    News & Views
    Nature
    Volume: 423, P: 493-495