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Showing 1–2 of 2 results
Advanced filters: Author: Jose Alberto Choreno-Parra Clear advanced filters

  • Khader and colleagues show Mycobacterium tuberculosis (Mtb)-specific B cells are needed to recruit TFH cells into follicular-like structures within lung granulomas to control the Mtb bacilli; however, specific antibodies and many conventional properties of B cells are dispensable.

    • Rosemary V. Swanson
    • Ananya Gupta
    • Shabaana A. Khader
    Research
    Nature Immunology
    Volume: 24, P: 855-868

  • Rosa et al. find that genes associated with Interferon (IFN) signaling, neutrophil degranulation and innate immune pathways are induced in the lungs of macaques in response to SARS-CoV-2 infection, whereas genes associated with collagen formation and regulation are reduced. Authors also note an overlap of genes associated with SARS-CoV-2 infection and tuberculosis, altogether providing new insights into the immunopathogenesis of COVID-19 disease.

    • Bruce A. Rosa
    • Mushtaq Ahmed
    • Shabaana A. Khader
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-14