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Showing 1–5 of 5 results
Advanced filters: Author: Josef Melcr Clear advanced filters

  • The inherent toxicity of the aromatic compounds to the chassis strain hampers further improvement of bioproduction. Here, the authors show that membrane rigidifying effect of resveratrol can be attenuated by exogenous supplementation of palmitelaidic acid or linoleic acid in fermentation of Corynebacterium glutamicum.

    • Apilaasha Tharmasothirajan
    • Josef Melcr
    • Jan Marienhagen
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-14

  • The mechanism of action of the antibacterial tripeptide AMC-109 is unclear. Here, Melcrová et al. show that AMC-109 self-assembles into stable aggregates with a cationic surface, and then individual peptides insert into the bacterial membrane and disrupt membrane nanodomains, thus affecting membrane function without forming pores.

    • Adéla Melcrová
    • Sourav Maity
    • Wouter H. Roos
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-13

  • Expanding on their previous work, Bondar et al present open source software tools to reliably quantify linear dichroism and determine molecular orientations. They demonstrate the utility of the tools by imaging synthetic lipid vesicles and as well as fluorescently labelled proteins in living cells

    • Alexey Bondar
    • Olga Rybakova
    • Josef Lazar
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-12