Nature Search

Deep brain stimulation of symptom-specific networks in Parkinson’s disease

Different motor symptoms respond variably to deep brain stimulation in Parkinson’s Disease. Rajamani et al. suggest that this variability may be due to tremor, bradykinesia, rigidity, and axial symptoms being associated with a gradient of brain circuits.

Nanditha Rajamani
Helen Friedrich
Andreas Horn
ResearchOpen Access31 May 2024
Nature Communications

Volume: 15, P: 1-16
Cloning and expression of the essential gene for poly(A) polymerase from S. cerevisiae

Joachim Lingner
Josef Kellermann
Walter Keller
Research12 Dec 1991
Nature

Volume: 354, P: 496-498
Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS

Plasma extracellular vesicles contain quantifiable amounts of TDP-43 and full-length tau, allowing the accurate assessment of pathology in frontotemporal dementia, frontotemporal dementia spectrum disorders and amyotrophic lateral sclerosis.

Madhurima Chatterjee
Selcuk Özdemir
Anja Schneider
ResearchOpen Access18 Jun 2024
Nature Medicine

Volume: 30, P: 1771-1783
Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage

Obtaining data on antimicrobial resistance (AMR) from healthy human populations is difficult. Here, Hendriksen et al. use metagenomic analysis to obtain AMR data from untreated sewage from 79 sites in 60 countries, finding correlations with socio-economic, health and environmental factors.

Rene S. Hendriksen
Patrick Munk
Frank M. Aarestrup
ResearchOpen Access08 Mar 2019
Nature Communications

Volume: 10, P: 1-12
Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models

Clinical multi-omics data are integrated and analyzed using a generative deep-learning model.

Rosa Lundbye Allesøe
Agnete Troen Lundgaard
Moustafa Abdalla
ResearchOpen Access02 Jan 2023
Nature Biotechnology

Volume: 41, P: 399-408
Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits

Many genetic variants have been associated with human traits, but the mechanism is often unknown. Here, the authors integrate local and distal genetic associations with multi-omics datasets to provide a roadmap to understand the underlying mechanisms of GWAS variants on complex traits.

Andrew A. Brown
Juan J. Fernandez-Tajes
Ana Viñuela
ResearchOpen Access21 Aug 2023
Nature Communications

Volume: 14, P: 1-17
A reference map of potential determinants for the human serum metabolome

The levels of 1,251 metabolites are measured in 475 phenotyped individuals, and machine-learning algorithms reveal that diet and the microbiome are the determinants with the strongest predictive power for the levels of these metabolites.

Noam Bar
Tal Korem
Eran Segal
Research11 Nov 2020
Nature

Volume: 588, P: 135-140
Author Correction: Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models

Rosa Lundbye Allesøe
Agnete Troen Lundgaard
Moustafa Abdalla
Amendments and CorrectionsOpen Access02 May 2023
Nature Biotechnology

Volume: 41, P: 1026
Effects of metazachlor and its major metabolite metazachlor OA on early life stages of marbled crayfish

Josef Velisek
Alzbeta Stara
Antonin Kouba
ResearchOpen Access21 Jan 2020
Scientific Reports

Volume: 10, P: 1-9
Insights from biochemical reconstitution into the architecture of human kinetochores

Biochemical reconstitution of a synthetic human kinetochore with 21 protein subunits and centromeric nucleosomal DNA unveils fundamental principles of kinetochore organization and function.

John R. Weir
Alex C. Faesen
Andrea Musacchio
Research31 Aug 2016
Nature

Volume: 537, P: 249-253
Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse

A low-coverage draft genome sequence from a horse bone recovered from permafrost dated to approximately 560–780 thousand years ago is presented; this represents the oldest full genome sequence to date by almost an order of magnitude.

Ludovic Orlando
Aurélien Ginolhac
Eske Willerslev
Research26 Jun 2013
Nature

Volume: 499, P: 74-78
Radiosensitivity in breast cancer assessed by the Comet and micronucleus assays

C S Djuzenova
B Mühl
M Flentje
ResearchOpen Access14 Mar 2006
British Journal of Cancer

Volume: 94, P: 1194-1203
Data integration for prediction of weight loss in randomized controlled dietary trials

Rikke Linnemann Nielsen
Marianne Helenius
Ramneek Gupta
ResearchOpen Access18 Nov 2020
Scientific Reports

Volume: 10, P: 1-15
An essential developmental function for murine phosphoglycolate phosphatase in safeguarding cell proliferation

Gabriela Segerer
Kerstin Hadamek
Antje Gohla
ResearchOpen Access12 Oct 2016
Scientific Reports

Volume: 6, P: 1-13
Adenovirus early E4 genes in viral oncogenesis

Birgitt Täuber
Thomas Dobner
Reviews28 Nov 2001
Oncogene

Volume: 20, P: 7847-7854
Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data

James H. R. Farmery
Mike L. Smith
Andy G. Lynch
ResearchOpen Access22 Jan 2018
Scientific Reports

Volume: 8, P: 1-17
Publisher Correction: Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data

James H. R. Farmery
Mike L. Smith
Andy G. Lynch
Amendments and CorrectionsOpen Access03 Sept 2018
Scientific Reports

Volume: 8, P: 1-4

Search

Deep brain stimulation of symptom-specific networks in Parkinson’s disease

Cloning and expression of the essential gene for poly(A) polymerase from S. cerevisiae

Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS

Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage

Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models

Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits

A reference map of potential determinants for the human serum metabolome

Author Correction: Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models

Effects of metazachlor and its major metabolite metazachlor OA on early life stages of marbled crayfish

Insights from biochemical reconstitution into the architecture of human kinetochores

Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse

Radiosensitivity in breast cancer assessed by the Comet and micronucleus assays

Data integration for prediction of weight loss in randomized controlled dietary trials

An essential developmental function for murine phosphoglycolate phosphatase in safeguarding cell proliferation

Adenovirus early E4 genes in viral oncogenesis

Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data

Publisher Correction: Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data

Search

Quick links

Search

Filter By:

Search

Quick links