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Pediatric Research (29)
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Showing 1–50 of 59 results

Advanced filters: Author: Joseph D Schulman Clear advanced filters

Pantetheinase Activity and Cysteamine Content in Cystinotic and Normal Fibroblasts and Leukocytes

Sheldon Orloff
Jean Deb Butler
Joseph D Schulman
Research01 Jul 1981
Pediatric Research

Volume: 15, P: 1063-1067
Biochemical, Morphologic, and Gytogenetic Studies of Leukocytes Growing in Continuous Culture from Normal Individuals and from Patients with Cystinosis

Joseph D Schulman
Kathryn H Bradley
Matti S Al-Aish
Research01 Oct 1971
Pediatric Research

Volume: 5, P: 501-510
Placental Transfer of Analogs of Glucose and Amino Acids in Experimental Intrauterine Growth Retardation

Menachem Nitzan
Sheldon Orloff
Joseph D Schulman
Research01 Feb 1979
Pediatric Research

Volume: 13, P: 100-103
Effect of Homocysteine and Homocystine on Platelet and Vascular Arachidonic Acid Metabolism

Janet E Graeber
Jeffrey H Slott
Marie J Stuart
Research01 Jun 1982
Pediatric Research

Volume: 16, P: 490-493
Occurrence of 4-Amino-5-imidazolecarboxamide as a Pentose Derivative

JOSEPH S. GOTS
Research08 Aug 1953
Nature

Volume: 172, P: 256-257
γ-Glutamyl Transferase: Studies of Normal and Cystinotic Human Leukocytes, Rabbit Neutrophiles, and Rat Liver

A Desmond Patrick
Richard D Berlin
Joseph D Schulman
Research01 Sept 1979
Pediatric Research

Volume: 13, P: 1058-1064
Rational design of potent sialidase-based inhibitors of influenza virus replication

Mark von Itzstein
Wen-Yang Wu
Charles R. Penn
Research03 Jun 1993
Nature

Volume: 363, P: 418-423
Recent Advances in Reproductive Genetic Technologies

Gene Levinson
Carolyn B. Coulam
Joseph D. Schulman
Reviews01 Sept 1995
Bio/Technology

Volume: 13, P: 968-973
Mauve Factor re-identified as 2,4-Dimethyl-3-ethylpyrrole and its Sedative Effect on the CNS

ARTHUR SOHLER
RAYMOND BECK
JOSEPH J. NOVAL
Research26 Dec 1970
Nature

Volume: 228, P: 1318-1320
Measurement of the in vivo Degradation of Carbon-14-labelled Thymidine and Its Halogenated Analogues in Man by Continuous Monitoring of Expired Carbon-14-Carbon Dioxide

JOSEPH P. KRISS
RICHARD K. SHAW
NIKKI EDMUNDS
Research06 Jun 1964
Nature

Volume: 202, P: 1021
A NEW SYNDROME OF HYPERURICEMIA, PULMONARY FIBROSIS, AND RENAL DISEASE IN A KINDRED

Sheldon Orloff
Bruce Mcdonald
Joseph P Schulman
Research01 Apr 1977
Pediatric Research

Volume: 11, P: 461
GLUCOSURIA AND UNUSUAL AMINOACIDURIA

Sheldon Orloff
Stephen P Spielberg
Joseph D Schulman
Research01 Apr 1977
Pediatric Research

Volume: 11, P: 461
Adenine Therapy for Lesch-Nyhan Syndrome

Joseph D Schulman
Martin L Greene
J Edwin Seegmiller
Research01 Feb 1971
Pediatric Research

Volume: 5, P: 77-82
Depletion of Cystine in Cystinotic Fibroblasts by Drugs Enclosed in Liposomes

Jean Debrohun Butler
Frank Tietze
Joseph D Schulman
Research01 Jan 1978
Pediatric Research

Volume: 12, P: 46-51
Interaction between Protein Sulphydryl Groups and Lipid Double Bonds in Biological Membranes

JOSEPH D. ROBINSON
Research08 Oct 1966
Nature

Volume: 212, P: 199-200
Decreased Binding of ¹⁴C-Homogentisic Acid induced by Ascorbic Acid in Connective Tissues of Rats with Experimental Alcaptonuria

THOMAS J. LUSTBERG
JOSEPH D. SCHULMAN
J. EDWIN SEEGMILLER
Research21 Nov 1970
Nature

Volume: 228, P: 770-771
The small CRL4^CSA ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics

Transcription-Coupled Nucleotide Excision Repair (TC-NER) removes transcription-blocking DNA lesions. This study reveals that DDA1 is a crucial player in TC-NER, protecting transcription programs against genotoxic insults.

Diana A. Llerena Schiffmacher
Shun-Hsiao Lee
Alex Pines
ResearchOpen Access29 Jul 2024
Nature Communications

Volume: 15, P: 1-17
Identification of disease-linked hyperactivating mutations in UBE3A through large-scale functional variant analysis

UBE3A gene dysregulation is associated with neurodevelopmental disorders, but predicting the function of UBE3A variants remains difficult. The authors use a high-throughput assay to categorize variants by functional activity, and show that UBE3A hyperactivity increases the risk of neurodevelopmental disease.

Kellan P. Weston
Xiaoyi Gao
Jason J. Yi
ResearchOpen Access23 Nov 2021
Nature Communications

Volume: 12, P: 1-15
“Thinking Upstream” to Evaluate and to Improve the Daily Work of the Newborn Intensive Care Unit

Joseph Schulman
Comments & Opinion04 Sept 2001
Journal of Perinatology

Volume: 21, P: 307-311
High brain densities of the immunophilin FKBP colocalized with calcineurin

Joseph P. Steiner
Ted M. Dawson
Solomon H. Snyder
Research13 Aug 1992
Nature

Volume: 358, P: 584-587
Heteromeric clusters of ubiquitinated ER-shaping proteins drive ER-phagy

The membrane-shaping protein ARL6IP1 is involved in the selective degradation of the endoplasmic reticulum, and this process depends on its ubiquitination and interaction with other membrane-shaping proteins such as FAM134B.

Hector Foronda
Yangxue Fu
Christian A. Hübner
ResearchOpen Access24 May 2023
Nature

Volume: 618, P: 402-410
175 THE EFFECTS OF INTRAUTERINE GROWTH RETARDATION (IUGR ON FETAL LUNG CHOLINE KINASE ACTIVITY

Barbara L Chrzanowska
Rodney E Ulane
Joseph P Schulman
Research01 Apr 1978
Pediatric Research

Volume: 12, P: 393
Aramchol in patients with nonalcoholic steatohepatitis: a randomized, double-blind, placebo-controlled phase 2b trial

In a phase 2b study, inhibition of hepatic stearoyl-CoA desaturase in patients with nonalcoholic steatohepatitis was safe and tolerated; although reductions in liver fat were not significant, changes in liver enzymes and histology were observed.

V. Ratziu
L. de Guevara
Arun J. Sanyal
Research07 Oct 2021
Nature Medicine

Volume: 27, P: 1825-1835
Recognizing technique variation in rock engravings: ArchCUT3-D for micromorphological analysis

Lena Dubinsky
Marcelo David
Leore Grosman
ResearchOpen Access10 Jun 2023
Humanities and Social Sciences Communications

Volume: 10, P: 1-20
The Incidence of Seizures after Rehydration of Hypernatremic Rabbits with Intravenous or ad Libitum Oral Fluids

Gwendolyn R Hogan
Philip R Dodge
Susan Master
Research01 Apr 1984
Pediatric Research

Volume: 18, P: 340-345
1126 AN IMBALANCE IN PLATELET-VASCULAR PROSTAGLANDIN SYNTHESIS INDUCED BY HOMOCYSTEINE (HC) AND HOMOCYSTEIC ACID (HCA)

Janet E Graeber
Marie J Stuart
Joseph P Schulman
Research01 Apr 1981
Pediatric Research

Volume: 15, P: 630
564 TREATMENT OF GLUTATHIONE SYNTHETASE DEFICIENT FIBROBLASTS BY INHIBITION OF γ-GLUTAMYL TRANSPEPTIDASE WITH SERINE-BORATE

Stephen P Spielberg
Jean Deb. Butler
Joseph D Schulman
Research01 Apr 1978
Pediatric Research

Volume: 12, P: 457
386 TSH HYPERSECRETION AND TSHα AND TSHβ SUBUNIT MEASUREMENTS IN NEPHROPATHIC CYSTINOSIS

Barry B Bercu
Joseph D Schulman
Research01 Apr 1981
Pediatric Research

Volume: 15, P: 504
VITAMIN E PROPHYLAXIS IN NEONATAL PHYSIOLOGIC AND G6PD DEFICIENCY HYPERBILIRUBINEMIA

Arthur I Eidelman
Matti Ehrlichman
Larry Corash
Research01 Apr 1984
Pediatric Research

Volume: 18, P: 345
MILK TRANSPORT OF [³H]MELATONIN TO SUCKLING RATS

Steven M Reppert
David C Klein
Joseph D Schulman
Research01 Apr 1977
Pediatric Research

Volume: 11, P: 420
Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler

Using synthetic ubiquitins with non-natural acceptor site, the authors revealed that the length of lysine side chain in acceptor ubiquitins affects ubiquitin chain linkage specificity with native lysine as the preferred geometry.

Joanna Liwocha
David T. Krist
Brenda A. Schulman
Research07 Dec 2020
Nature Chemical Biology

Volume: 17, P: 272-279
A PREDICTIVE SCORE FOR THE MANAGEMENT OF THE RESPIRATORY DISTRESS SYNDROME (RDS)

George J Peckham
Joseph Schulman
Jean A Cortner
Research01 Apr 1977
Pediatric Research

Volume: 11, P: 577
A Novel Process for the Large-Scale Purification of Recombinant Tick Anticoagulant Peptide Using Perfusion Chromatography

E. Dale Lehman
Joseph G. Joyce
William J. Miller
Research01 Feb 1993
Bio/Technology

Volume: 11, P: 207-212
HYPERAMMONEMIA WITH PARTIAL CARBAMYL PHOSPHATE SYNTHASE (CPS) DEFICIENCY RESPONSIVE TO ARGININE THERAPY

Allen M Glasgow
Sheldon Orloff
Joseph P Schulman
Research01 Apr 1977
Pediatric Research

Volume: 11, P: 456
THE MURINE Ah LOCUS AND DYSMORPHOGENESIS

Shu Shum
George H Lambert
Joseph Schulman
Research01 Apr 1977
Pediatric Research

Volume: 11, P: 529
1167 ADRENOLEUKODYSTROPHY: ABOVE NORMAL LEVELS OF VERY LONG CHAIN FATTY ACIDS IN PLASMA

Hugo W Moser
Ann E Moser
J F Kennedy
Research01 Apr 1981
Pediatric Research

Volume: 15, P: 637
1125 DELAY IN DEGRADATION OF PULMONARY GLYCOGEN IN FETUSES OF STREPTOZOTOCIN-DIABETIC RATS

Ira H Gewolb
Carolyn Barrett
Joseph B Warshaw
Research01 Apr 1981
Pediatric Research

Volume: 15, P: 630
AMINO ACID METABOLISM IN DYSMATURE NEWBORN RATS: POSSIBLE EXPLANATION FOR THE ANTIHYPOGLYCEMIC EFFECT OF PRENATAL GLUCOCORTICOIDS

Robert L Manniello
Joseph D Schulman
Nich D Bethesda
Research01 Apr 1977
Pediatric Research

Volume: 11, P: 409
HYPERPHENYLALANINEMIA DUE TO PHENYLALANINE HYDROXYLASE COFACTOR DEFICIENCY

Sheldon Milstien
Sheldon Orloff
Seymour Kaufman
Research01 Apr 1977
Pediatric Research

Volume: 11, P: 460
Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia

The RNA binding protein MUSASHI-2 (MSI2) is a potential therapeutic target for acute myeloid leukemia. Here the authors identify a small molecule inhibitor of MSI2 and characterize its effects in a murine leukemia model.

Gerard Minuesa
Steven K. Albanese
Michael G. Kharas
ResearchOpen Access19 Jun 2019
Nature Communications

Volume: 10, P: 1-15
Evaluation of Adenine Therapy for Lesch-Nyhan Syndrome

Joseph D Schulman
Martin L Greene
W L Nyhan
Research01 Sept 1970
Pediatric Research

Volume: 4, P: 452-453
GWAS meta-analysis of intrahepatic cholestasis of pregnancy implicates multiple hepatic genes and regulatory elements

Investigation of variation in three cohorts has identified multiple genetic signals associated with the pregnancy-specific liver disorder, intrahepatic cholestasis of pregnancy, giving insight into the disease which can cause preterm birth and stillbirth.

Peter H. Dixon
Adam P. Levine
Catherine Williamson
ResearchOpen Access17 Aug 2022
Nature Communications

Volume: 13, P: 1-18
Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

Classically activated macrophages are targets of intracellular bacteria such as Mycobacteria tuberculosis. Murray and colleagues find that such pathogens induce arginase 1 in these macrophages to block the production of antibacterial nitric oxide.

Karim C El Kasmi
Joseph E Qualls
Peter J Murray
Research02 Nov 2008
Nature Immunology

Volume: 9, P: 1399-1406
Whole-genome sequencing of patients with rare diseases in a national health system

Whole-genome sequencing and phenotype data sharing are introduced in a national health system to streamline diagnosis and to discover coding and non-coding variants that cause rare diseases.

Ernest Turro
William J. Astle
Willem H. Ouwehand
Research24 Jun 2020
Nature

Volume: 583, P: 96-102
873 SPONTANEOUS TRANSFORMATION OF CULTURED SKIN FIBROBLASTS INTO OSTEOBLASTS IN A CASE OF DYSPLASTIC INTRA DERMAL CALCIFICATION

Mary O Lim
Anil B Mukherjee
Joseph D Schulman
Research01 Apr 1978
Pediatric Research

Volume: 12, P: 509
DECREASE IN HEPATIC LIPOGENESIS IN TERM RAT LIVER EXPLANTS

William M Maniscalco
Ian Gross
Joseph B Warshaw
Research01 Apr 1977
Pediatric Research

Volume: 11, P: 409
Essential role of calcium in the regulation of MAP kinase phosphatase-1 expression

Jean-Claude Scimeca
Marc J Servant
Sylvain Meloche
Research07 Aug 1997
Oncogene

Volume: 15, P: 717-725
1561 MEZLOCILLIN (MEZ) VS. CONVENTIONAL BINATION ANTI-MICROBIAL THERAPY FOR PREMATURE INFANTS ADMITTED TO AN INTENSIVE CARE NURSERY (ICN)

Frederick H Wirth
Thomas Rubio
Joseph Schutoian
Research01 Apr 1985
Pediatric Research

Volume: 19, P: 371
NO is necessary and sufficient for egg activation at fertilization

Richard C. Kuo
Gregory T. Baxter
David Epel
Research10 Aug 2000
Nature

Volume: 406, P: 633-636
Changes in IGF-I and -II, IGF Binding Protein, and IGF Receptor Transcript Abundance after Uterine Artery Ligation

Wayne A Price
Liu Rong
A Joseph D'ercole
Research01 Sept 1992
Pediatric Research

Volume: 32, P: 291-295

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