Nature Search

Mac-1 (CD11b/CD18) is an oligodeoxynucleotide-binding protein

Lyuba Benimetskaya
John D. Loike
C.A. Stein
Research01 Apr 1997
Nature Medicine

Volume: 3, P: 414-420
A benchmark of expert-level academic questions to assess AI capabilities

Humanity’s Last Exam, a multi-modal benchmark at the frontier of human knowledge, is designed to be an expert-level closed-ended academic benchmark with broad subject coverage.

Long Phan
Alice Gatti
Davide Scaramuzza
ResearchOpen Access28 Jan 2026
Nature

Volume: 649, P: 1139-1146
Scavenger receptor-mediated adhesion of microglia to β-amyloid fibrils

Joseph El Khoury
Suzanne E. Hickman
John D. Loike
Research22 Aug 1996
Nature

Volume: 382, P: 716-719
Functional genomics and tumor microenvironment analysis reveal prognostic biological subtypes in Mantle cell lymphoma

Mantle cell lymphoma (MCL) is a form of B-cell non-Hodgkin lymphoma with a high degree of genetic and clinical heterogeneity. Here, using a multi-omics approach, the authors investigate genetic alterations in association with the tumour microenvironment to identify potential therapeutic vulnerabilities.

Sunandini Sharma
Roshia Ali
Javeed Iqbal
ResearchOpen Access05 Nov 2025
Nature Communications

Volume: 16, P: 1-21
Clinicopathologic spectrum of myeloid neoplasms with concurrent myeloproliferative neoplasm driver mutations and SRSF2 mutations

Mehrnoosh Tashakori
Joseph D. Khoury
Sanam Loghavi
Research11 Jun 2022
Modern Pathology

Volume: 35, P: 1677-1683
Scara1 deficiency impairs clearance of soluble amyloid-β by mononuclear phagocytes and accelerates Alzheimer’s-like disease progression

The scavenger receptor Scara1, expressed on microglia and macrophages, binds beta amyloid aggregates. In a mouse model of Alzheimer’s disease, the authors show that Scara1deficiency is associated with reduced clearance and increased deposition of aggregates in the brain, which results in early mortality.

Dan Frenkel
Kim Wilkinson
Joseph El Khoury
Research25 Jun 2013
Nature Communications

Volume: 4, P: 1-9
Acquired WT1 mutations contribute to relapse of NPM1-mutated acute myeloid leukemia following allogeneic hematopoietic stem cell transplant

Siba El Hussein
Courtney D. DiNardo
Sanam Loghavi
Research07 Jan 2022
Bone Marrow Transplantation

Volume: 57, P: 370-376
Artificial intelligence-assisted mapping of proliferation centers allows the distinction of accelerated phase from large cell transformation in chronic lymphocytic leukemia

Siba El Hussein
Pingjun Chen
Joseph D. Khoury
Research07 Feb 2022
Modern Pathology

Volume: 35, P: 1121-1125
Neural markers of attention processing in pediatric cochlear implant users: an ERP study

Ola Badarni-Zahalka
Ornella Dakwar-Kawar
Cahtia Adelman
ResearchOpen Access28 Oct 2025
Scientific Reports

Volume: 15, P: 1-15
Prevalence of Iron deficiency in Lebanese schoolchildren

Ralph El Khoury
Ghassan Sleilaty
Marie-Hélène Gannagé-Yared
Research03 Mar 2020
European Journal of Clinical Nutrition

Volume: 74, P: 1157-1163
Usefulness of the genetic risk score to identify phenocopies in families with familial hypercholesterolemia?

Youmna Ghaleb
Sandy Elbitar
Mathilde Varret
Research26 Jan 2018
European Journal of Human Genetics

Volume: 26, P: 570-578
CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

The molecular mechanisms behind recognition of altered self remain unclear. Moore and co-workers show that oxidized low-density lipoprotein (LDL) and β-amyloid trigger inflammatory signaling through a heterodimer of Toll-like receptors 4 and 6.

Cameron R Stewart
Lynda M Stuart
Kathryn J Moore
Research27 Dec 2009
Nature Immunology

Volume: 11, P: 155-161
Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease

Joseph El Khoury
Michelle Toft
Andrew D Luster
Research11 Mar 2007
Nature Medicine

Volume: 13, P: 432-438
The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity

Failure to clear apoptotic cells can lead to autoinflammatory disease. Means and colleagues demonstrate that the receptor SCARF1 recognizes C1q-bound apoptotic cells, which leads to their clearance and prevents lupus-like symptoms.

Zaida G Ramirez-Ortiz
William F Pendergraft III
Terry K Means
Research28 Jul 2013
Nature Immunology

Volume: 14, P: 917-926
The receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunity

Fine-tuning of TLR7 signaling modulates innate inflammatory responses. Means and colleagues identify the receptor TREML4 as an essential positive regulator of TLR7 signaling during antiviral responses and autoimmunity.

Zaida G Ramirez-Ortiz
Amit Prasad
Terry K Means
Research06 Apr 2015
Nature Immunology

Volume: 16, P: 495-504
Neurodegeneration and the neuroimmune system

Joseph El Khoury
Correspondence06 Dec 2010
Nature Medicine

Volume: 16, P: 1369-1370
GlioM&M: Web-based tool for studying circulating and infiltrating monocytes and macrophages in glioma

Erik R. Abels
Sybren L. N. Maas
Joseph El Khoury
ResearchOpen Access18 Jun 2020
Scientific Reports

Volume: 10, P: 1-11
Prevalence and pattern of comorbidities in chronic rheumatic and musculoskeletal diseases: the COMORD study

Nelly Ziade
Bernard El Khoury
Jamil Messaykeh
ResearchOpen Access06 May 2020
Scientific Reports

Volume: 10, P: 1-10
Next-Generation Scholarship: Rebranding Hematopathology Using Twitter: The MD Anderson Experience

Siba El Hussein
Joseph D. Khoury
Sanam Loghavi
Editorial20 Nov 2020
Modern Pathology

Volume: 34, P: 854-861
The microglial sensome revealed by direct RNA sequencing

In this Resource study, the authors used Direct RNA Sequencing (DRS) to quantitatively examine the transcriptional profile of microglia, focusing specifically on the proteins important for binding endogenous ligands and potential pathogens—a collection they term the 'sensome'. They also compare this profile to that of peripheral macrophages.

Suzanne E Hickman
Nathan D Kingery
Joseph El Khoury
Research27 Oct 2013
Nature Neuroscience

Volume: 16, P: 1896-1905
Genetic inhibition of RIPK3 ameliorates functional outcome in controlled cortical impact independent of necroptosis

Limin Wu
Joon Yong Chung
Michael J. Whalen
ResearchOpen Access09 Nov 2021
Cell Death & Disease

Volume: 12, P: 1-16
Microglia in neurodegeneration

Microglia are the sentinels, housekeepers, and defenders of the brain. In this review we consider the immune checkpoints that control microglial functions and discuss how their imbalance and subsequent neuroinflammation leads to neurodegeneration.

Suzanne Hickman
Saef Izzy
Joseph El Khoury
Reviews26 Sept 2018
Nature Neuroscience

Volume: 21, P: 1359-1369
New Sequencing technologies help revealing unexpected mutations in Autosomal Dominant Hypercholesterolemia

Sandy Elbitar
Delia Susan-Resiga
Marianne Abifadel
ResearchOpen Access31 Jan 2018
Scientific Reports

Volume: 8, P: 1-10
Pathogenic variants in THSD4, encoding the ADAMTS-like 6 protein, predispose to inherited thoracic aortic aneurysm

Sandy Elbitar
Marjolijn Renard
Marianne Abifadel
Research28 Aug 2020
Genetics in Medicine

Volume: 23, P: 111-122
Minimum and optimal numbers of psychiatric beds: expert consensus using a Delphi process

Adrian P. Mundt
Enzo Rozas Serri
Stefan Priebe
Reviews21 Jan 2022
Molecular Psychiatry

Volume: 27, P: 1873-1879
Targeting Bacterial Cardiolipin Enriched Microdomains: An Antimicrobial Strategy Used by Amphiphilic Aminoglycoside Antibiotics

Micheline El Khoury
Jitendriya Swain
Marie-Paule Mingeot-Leclercq
ResearchOpen Access06 Sept 2017
Scientific Reports

Volume: 7, P: 1-12

Search

Mac-1 (CD11b/CD18) is an oligodeoxynucleotide-binding protein

A benchmark of expert-level academic questions to assess AI capabilities

Scavenger receptor-mediated adhesion of microglia to β-amyloid fibrils

Functional genomics and tumor microenvironment analysis reveal prognostic biological subtypes in Mantle cell lymphoma

Clinicopathologic spectrum of myeloid neoplasms with concurrent myeloproliferative neoplasm driver mutations and SRSF2 mutations

Scara1 deficiency impairs clearance of soluble amyloid-β by mononuclear phagocytes and accelerates Alzheimer’s-like disease progression

Acquired WT1 mutations contribute to relapse of NPM1-mutated acute myeloid leukemia following allogeneic hematopoietic stem cell transplant

Artificial intelligence-assisted mapping of proliferation centers allows the distinction of accelerated phase from large cell transformation in chronic lymphocytic leukemia

Neural markers of attention processing in pediatric cochlear implant users: an ERP study

Prevalence of Iron deficiency in Lebanese schoolchildren

Usefulness of the genetic risk score to identify phenocopies in families with familial hypercholesterolemia?

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease

The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity

The receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunity

Neurodegeneration and the neuroimmune system

GlioM&M: Web-based tool for studying circulating and infiltrating monocytes and macrophages in glioma

Prevalence and pattern of comorbidities in chronic rheumatic and musculoskeletal diseases: the COMORD study

Next-Generation Scholarship: Rebranding Hematopathology Using Twitter: The MD Anderson Experience

The microglial sensome revealed by direct RNA sequencing

Genetic inhibition of RIPK3 ameliorates functional outcome in controlled cortical impact independent of necroptosis

Microglia in neurodegeneration

New Sequencing technologies help revealing unexpected mutations in Autosomal Dominant Hypercholesterolemia

Pathogenic variants in THSD4, encoding the ADAMTS-like 6 protein, predispose to inherited thoracic aortic aneurysm

Minimum and optimal numbers of psychiatric beds: expert consensus using a Delphi process

Targeting Bacterial Cardiolipin Enriched Microdomains: An Antimicrobial Strategy Used by Amphiphilic Aminoglycoside Antibiotics

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