This study examines neuronal activity coupling between the medial prefrontal cortex (mPFC), basolateral amygdala (BLA) and hippocampus during the recall phase of a differential fear conditioning task and during exposure to a novel open field. The authors show that theta frequency power and synchrony between the mPFC and BLA increase with successful discrimination of aversive versus safe cues, and that the mPFC activity leads that in the BLA during safety.
- Ekaterina Likhtik
- Joseph M Stujenske
- Joshua A Gordon
