The glomerulus, unlike many capillary beds, readily supports leukocyte recruitment, but little is known about the actions of leukocytes upon recruitment to glomeruli. Devi and colleagues have addressed this issue with a multiphoton, confocal microscopy–based approach to shed light on glomerular inflammation. Induction of inflammation in mice did not increase the number of leukocytes recruited to glomeruli but prolonged the duration of leukocyte retention and migration.
- Sapna Devi
- Anqi Li
- Michael J Hickey