Nature Search

Nuclear accumulation of FGF-2 is associated with proliferation of human astrocytes and glioma cells

A Joy
J Moffet
M K Stachowiak
Research16 Jan 1997
Oncogene

Volume: 14, P: 171-183
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Erratum: Identification of globular mechanochemical heads of kinesin

Jonathan M. Scholey
John Heuser
Lawrence S. B. Goldstein
Amendments and Corrections20 Apr 1989
Nature

Volume: 338, P: 666
Correction: Corrigendum: Mitochondrial gene replacement in primate offspring and embryonic stem cells

Masahito Tachibana
Michelle Sparman
Shoukhrat Mitalipov
Amendments and Corrections10 Dec 2014
Nature

Volume: 516, P: 276
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Mitochondrial gene replacement in primate offspring and embryonic stem cells

The mitochondrial genome is of maternal origin and mutations in mitochondrial DNA are the cause of many human diseases. The efficient replacement of the mitochondrial genome in mature non-human primate oocytes is now demonstrated. This approach may offer a reproductive option to prevent the transmission of diseases caused by mutations in mitochondrial DNA in affected families.

Masahito Tachibana
Michelle Sparman
Shoukhrat Mitalipov
Research26 Aug 2009
Nature

Volume: 461, P: 367-372
A giant NLR gene confers broad-spectrum resistance to Phytophthora sojae in soybean

While multiple resistance-to-Phytophthora sojae loci/alleles have been mapped in soybean, many of them have become ineffective to newly evolved isolates. Here, the authors show that a 27.7-kb nucleotide-binding site-leucine-rich repeat gene confers broad-spectrum resistance to P. sojae in soybean.

Weidong Wang
Liyang Chen
Jianxin Ma
ResearchOpen Access05 Nov 2021
Nature Communications

Volume: 12, P: 1-8
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
Towards germline gene therapy of inherited mitochondrial diseases

Mutations in mitochondrial DNA cause a wide range of disorders in humans, with a high prevalence; here it is shown that the nucleus of an affected woman’s egg could be inserted into healthy donor egg cytoplasm by spindle transfer, allowing the birth of healthy offspring.

Masahito Tachibana
Paula Amato
Shoukhrat Mitalipov
Research24 Oct 2012
Nature

Volume: 493, P: 627-631
Late Holocene methane rise caused by orbitally controlled increase in tropical sources

The source of what seems to be an anomalous increase in atmospheric methane concentrations about 5,000 years ago compared to methane levels during previous interglacial periods has puzzled researchers. Possible explanations for the rise in methane levels include very early agricultural activity. Climate and wetland simulations of global methane levels over the last glacial cycle now suggest that the increase in methane concentrations can be explained by natural changes in the Earth's orbital configuration, with enhanced emissions in the Southern Hemisphere tropics linked to precession-induced modification of seasonal precipitation

Joy S. Singarayer
Paul J. Valdes
David J. Beerling
Research02 Feb 2011
Nature

Volume: 470, P: 82-85
Effect of Tryptophan Treatment on Self-Biting and Central Nervous System Serotonin Metabolism in Rhesus Monkeys (Macaca mulatta)

Katherine P Weld
Joy A Mench
J Dee Higley
Research01 Oct 1998
Neuropsychopharmacology

Volume: 19, P: 314-321

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Nuclear accumulation of FGF-2 is associated with proliferation of human astrocytes and glioma cells

GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erratum: Identification of globular mechanochemical heads of kinesin

Correction: Corrigendum: Mitochondrial gene replacement in primate offspring and embryonic stem cells

A second update on mapping the human genetic architecture of COVID-19

Mitochondrial gene replacement in primate offspring and embryonic stem cells

A giant NLR gene confers broad-spectrum resistance to Phytophthora sojae in soybean

Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Towards germline gene therapy of inherited mitochondrial diseases

Late Holocene methane rise caused by orbitally controlled increase in tropical sources

Effect of Tryptophan Treatment on Self-Biting and Central Nervous System Serotonin Metabolism in Rhesus Monkeys (Macaca mulatta)

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