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Showing 1–50 of 62 results

Advanced filters: Author: Ju Hee Ryu Clear advanced filters

Factors associated with shock-refractory prehospital cardiac arrest

Kyung Hun Yoo
Byuk Sung Ko
Hye Jee Joo
ResearchOpen Access18 Aug 2025
Scientific Reports

Volume: 15, P: 1-9
Identification of Gng8-expressing cell types in the MHb and IPN

Hyun-ju Lee
Tae-Ik Choi
Insop Shim
Research27 Oct 2021
Molecular Psychiatry

Volume: 26, P: 3665
Pharmacogenomic landscape of patient-derived tumor cells informs precision oncology therapy

Analysis of genomic and transcriptomic data from 462 patient-derived tumor cell (PDC) samples across 14 cancer types, along with pharmacological responses to 60 agents, indicates that PDC-derived drug sensitivities might be predictive of clinical response to targeted therapies.

Jin-Ku Lee
Zhaoqi Liu
Do-Hyun Nam
Research27 Sept 2018
Nature Genetics

Volume: 50, P: 1399-1411
Distinctive CD39⁺CD9⁺ lung interstitial macrophages suppress IL-23/Th17-mediated neutrophilic asthma by inhibiting NETosis

Interstitial macrophages (IM) are a specialised population of macrophage cells in the lungs which regulate lung inflammation. Here using mouse models, the authors show that a CD39⁺CD9⁺ IM population reduce IL-23/Th17 driven neutrophilic inflammation through suppression of NETosis.

Seunghan Han
Bomin Kim
Ji-Hwan Ryu
ResearchOpen Access04 Oct 2024
Nature Communications

Volume: 15, P: 1-18
Author Correction: A wireless haptic interface for programmable patterns of touch across large areas of the skin

Yei Hwan Jung
Jae-Young Yoo
John A. Rogers
Amendments and Corrections28 Aug 2022
Nature Electronics

Volume: 5, P: 621
Near-strain-free anode architecture enabled by interfacial diffusion creep for initial-anode-free quasi-solid-state batteries

Initially anode-free batteries with garnet-type solid-state electrolytes suffer from internal strain by repeated Li plating/stripping. Here, the authors propose a near-strain-free anode architecture for interfacial diffusion of Li metal that suppresses volume expansion during cycling.

Kwang Hee Kim
Myung-Jin Lee
Jong Hyeok Park
ResearchOpen Access27 Apr 2024
Nature Communications

Volume: 15, P: 1-10
The power of genetic diversity in genome-wide association studies of lipids

A genome-wide association meta-analysis study of blood lipid levels in roughly 1.6 million individuals demonstrates the gain of power attained when diverse ancestries are included to improve fine-mapping and polygenic score generation, with gains in locus discovery related to sample size.

Sarah E. Graham
Shoa L. Clarke
Cristen J. Willer
Research09 Dec 2021
Nature

Volume: 600, P: 675-679
A cross-sectional study of ophthalmologic examination findings in 5385 Koreans presenting with intermittent exotropia

Dae Hee Kim
Jae Ho Jung
Soon Young Cho
ResearchOpen Access24 Jan 2023
Scientific Reports

Volume: 13, P: 1-8
Thirty-year clinical experience in gamma knife radiosurgery for trigeminal schwannomas

Dong-Won Shin
Chunseng Ju
Young-Hoon Kim
ResearchOpen Access23 Aug 2022
Scientific Reports

Volume: 12, P: 1-9
RhoGAP domain-containing fusions and PPAPDC1A fusions are recurrent and prognostic in diffuse gastric cancer

Diffuse Gastric Cancer (DGC) is increasingly being considered separate to intestinal type gastric cancer; several fusions events have been reported as drivers of the disease but few of those have been subsequently validated. Here the authors perform RNA-seq on early-onset DGC patients who had not been treated with chemotherapy or radiation and identify a previously unknown fusion.

Hanna Yang
Dongwan Hong
Hark Kyun Kim
ResearchOpen Access25 Oct 2018
Nature Communications

Volume: 9, P: 1-13
Blockade of airway inflammation and hyper-responsiveness by an angiopoietin-1 variant, COMP-Ang1

Kyung Sun Lee
Ka Young Lee
Yong Chul Lee
ResearchOpen Access01 Dec 2007
Experimental & Molecular Medicine

Volume: 39, P: 733-745
Effects of the Th2-dominant milieu on allergic responses in Der f 1-activated mouse basophils and mast cells

Myung-hee Yi
Hyoung-Pyo Kim
Tai-Soon Yong
ResearchOpen Access16 May 2018
Scientific Reports

Volume: 8, P: 1-9
Regulating astrocytic activity in the dorsal striatum mitigates L-dopa-induced dyskinesia in Parkinson’s disease

Young-Kyoung Ryu
Hye-Yeon Park
Kyoung-Shim Kim
ResearchOpen Access22 Jul 2025
Scientific Reports

Volume: 15, P: 1-12
Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer’s Disease

Sphingosine kinase (SphK) converts sphingosine into lipids, and is implicated in inflammation. Here the authors show that SphK1 functions as an acetyltransferase, regulates microglial phagocytosis and is reduced in a model of Alzheimer’s Disease, such that its restoration ameliorates pathology

Ju Youn Lee
Seung Hoon Han
Hee Kyung Jin
ResearchOpen Access16 Apr 2018
Nature Communications

Volume: 9, P: 1-14
Developmental self-reactivity determines pathogenic Tc17 differentiation potential of naive CD8⁺ T cells in murine models of inflammation

The heterogeneity in naive CD8⁺ T cells is essential for diverse immune responses. Here the authors show that variations in developmental self-reactivity of CD8⁺ T cells influence their differentiation into T_c17 cells in inflammatory conditions.

Gil-Woo Lee
Young Ju Kim
Jae-Ho Cho
ResearchOpen Access04 Apr 2024
Nature Communications

Volume: 15, P: 1-16
Tapered self-expandable metallic stent optimized for Eustachian tube morphology in a porcine ET model

Jeon Min Kang
Song Hee Kim
Hong Ju Park
ResearchOpen Access24 Nov 2022
Scientific Reports

Volume: 12, P: 1-8
Prevalence and detection of low-allele-fraction variants in clinical cancer samples

High-throughput sequencing is used to identify somatic variants in cancer patients. Here, the authors perform panel-based profiling of 5095 clinical samples and demonstrate that many clinically-actionable variants have low variant allele fractions, requiring assays with high detection sensitivity.

Hyun-Tae Shin
Yoon-La Choi
Woong-Yang Park
ResearchOpen Access09 Nov 2017
Nature Communications

Volume: 8, P: 1-10
Stimulation of melanogenesis by scoparone in B16 melanoma cells

Jeong-yeh Yang
Jeung-hyun Koo
Jin-woo Park
Research01 Nov 2006
Acta Pharmacologica Sinica

Volume: 27, P: 1467-1473
Fine tuning of CpG spatial distribution with DNA origami for improved cancer vaccination

The spacing of ligands presented to cells can have a huge impact on cellular responses. DNA origami is used to block structures to control the distribution of Toll-like receptor ligands and optimize presentation in the activation of dendritic cells in cancer immunotherapy.

Yang C. Zeng
Olivia J. Young
William M. Shih
Research15 Mar 2024
Nature Nanotechnology

Volume: 19, P: 1055-1065
Sirolimus-eluting cobalt–chrome alloy stent suppresses stent-induced tissue hyperplasia in a porcine Eustachian tube model

Jeon Min Kang
Song Hee Kim
Hong Ju Park
ResearchOpen Access02 Mar 2022
Scientific Reports

Volume: 12, P: 1-8
Loss-of-function gs3 allele decreases methane emissions and increases grain yield in rice

Rice paddies are a source of the potent greenhouse gas methane. The authors demonstrate that a rice variety containing naturally lost function in the gene GS3 has reduced allocation of photosynthates to roots, which results in a reduction of methane emissions during growth.

Youngho Kwon
Ji-Yoon Lee
Choong-Min Ryu
ResearchOpen Access27 Nov 2023
Nature Climate Change

Volume: 13, P: 1329-1333
Automated severity scoring of atopic dermatitis patients by a deep neural network

Chul Hwan Bang
Jae Woong Yoon
Ji Hyun Lee
ResearchOpen Access15 Mar 2021
Scientific Reports

Volume: 11, P: 1-8
Author Correction: A cross-sectional study of ophthalmologic examination findings in 5385 Koreans presenting with intermittent exotropia

Dae Hee Kim
Jae Ho Jung
Soon Young Cho
Amendments and CorrectionsOpen Access14 Feb 2023
Scientific Reports

Volume: 13, P: 1
Regulation of habenular G-protein gamma 8 on learning and memory via modulation of the central acetylcholine system

Hyun-ju Lee
Tae-Ik Choi
Insop Shim
Research28 Sept 2020
Molecular Psychiatry

Volume: 26, P: 3737-3750
Self-reactivity controls functional diversity of naive CD8⁺ T cells by co-opting tonic type I interferon

There is heterogeneity in the response to self-ligands within the naïve CD8⁺ T cell pool and the consequences of this are unclear. Here the authors show subsets of naïve CD8⁺ T cells which differ in expression of Ly6C and CD5 and response to viral infection through regulation by type I IFN signalling.

Young-Jun Ju
Sung-Woo Lee
Jae-Ho Cho
ResearchOpen Access18 Oct 2021
Nature Communications

Volume: 12, P: 1-15
Oligolysine-based coating protects DNA nanostructures from low-salt denaturation and nuclease degradation

The instability of DNA nanostructures in physiological environments has hampered their use as therapeutics and diagnostic agents inin vivoapplications. Here, the authors show that coating DNA origami with oligolysine-PEG moieties improves their pharmacokinetic properties in mouse models.

Nandhini Ponnuswamy
Maartje M. C. Bastings
William M. Shih
ResearchOpen Access31 May 2017
Nature Communications

Volume: 8, P: 1-9
Ultrafast Method for Selective Design of Graphene Quantum Dots with Highly Efficient Blue Emission

Suk Hyun Kang
Sungwook Mhin
Kwang Bo Shim
ResearchOpen Access08 Dec 2016
Scientific Reports

Volume: 6, P: 1-7
Self-Limiting Layer Synthesis of Transition Metal Dichalcogenides

Youngjun Kim
Jeong-Gyu Song
Hyungjun Kim
ResearchOpen Access04 Jan 2016
Scientific Reports

Volume: 6, P: 1-8
A wireless haptic interface for programmable patterns of touch across large areas of the skin

A lightweight, flexible technology that displays vibro-tactile patterns across large areas of the skin in single units or through a wirelessly coordinated collection of them can be used to convey map directions for road navigation, translate musical tracks into tactile patterns and reconstruct tactile sensations for feedback control of robotic prosthetics.

Yei Hwan Jung
Jae-Young Yoo
John A. Rogers
Research23 May 2022
Nature Electronics

Volume: 5, P: 374-385
Comparison between norepinephrine plus epinephrine and norepinephrine plus vasopressin after return of spontaneous circulation in patients with out-of-hospital cardiac arrest

Sejoong Ahn
Bo-Yeong Jin
Ji Hoon Kim
ResearchOpen Access18 Apr 2025
Scientific Reports

Volume: 15, P: 1-11
Battery-free, wireless soft sensors for continuous multi-site measurements of pressure and temperature from patients at risk for pressure injuries

Uninterrupted monitoring of pressure and temperature at skin interfaces can help to minimize the potential for pressure injuries in hospitalized or bedridden patients. Here, the authors introduce a soft, skin-mountable sensor that can continuously provide readings via antennas mounted under bedding, and demonstrate the functionality and robustness of the devices on patients.

Yong Suk Oh
Jae-Hwan Kim
John A. Rogers
ResearchOpen Access24 Aug 2021
Nature Communications

Volume: 12, P: 1-16
Brain-type creatine kinase has a crucial role in osteoclast-mediated bone resorption

Brain-type creatine kinase (Ckb) has an unexpected role in bone biology. Decreasing its activity suppresses the bone-resorbing activity of osteoclasts, and mice lacking Ckb are protected from osteoporosis-inducing treatments. These findings identify Ckb as a new molecular against bone loss.

Eun-Ju Chang
Jeongim Ha
Hong-Hee Kim
Research24 Aug 2008
Nature Medicine

Volume: 14, P: 966-972
Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer’s disease via H₂O₂⁻ production

Chun et al. find that a severe model of reactive astrocytes overproduces hydrogen peroxide, leading to the development of Alzheimer’s disease-like pathologies, including neurodegeneration, tauopathy and memory impairment.

Heejung Chun
Hyeonjoo Im
C. Justin Lee
Research16 Nov 2020
Nature Neuroscience

Volume: 23, P: 1555-1566
Establishment of patient-derived xenografts from patients with gastrointestinal stromal tumors: analysis of clinicopathological characteristics related to engraftment success

Young-Soon Na
Min-Hee Ryu
Yoon-Koo Kang
ResearchOpen Access14 May 2020
Scientific Reports

Volume: 10, P: 1-8
Photobiomodulation therapy for diabetic erectile dysfunction targeting neuroinflammation and neurovascular regeneration

Limanjaya Anita
Min-Ji Choi
Ji-Kan Ryu
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-15
Molecular variations in Th1-specific cell surface gene Tim-3

Soo-Cheon Chae
Ju-Hee Song
Hun-Taeg Chung
ResearchOpen Access01 Jun 2004
Experimental & Molecular Medicine

Volume: 36, P: 274-278
Reduced oxidative capacity in macrophages results in systemic insulin resistance

M1-like polarization of macrophages is thought to control adipose inflammation and associated insulin resistance and metabolic syndrome. Here the authors show that macrophage-specific deletion of the OxPhos-related gene Crif1 results in an M1-like phenotype in mice, and that the effects can be reversed by recombinant GDF15.

Saet-Byel Jung
Min Jeong Choi
Minho Shong
ResearchOpen Access19 Apr 2018
Nature Communications

Volume: 9, P: 1-15
Alleviation of skin inflammation after Lin⁻ cell transplantation correlates with their differentiation into myeloid-derived suppressor cells

Su Jeong Ryu
Ji-Min Ju
Eun Young Choi
ResearchOpen Access06 Oct 2015
Scientific Reports

Volume: 5, P: 1-18
Author Correction: Battery-free, wireless soft sensors for continuous multi-site measurements of pressure and temperature from patients at risk for pressure injuries

Yong Suk Oh
Jae-Hwan Kim
John A. Rogers
Amendments and CorrectionsOpen Access18 Nov 2021
Nature Communications

Volume: 12, P: 1
Physician adherence and patient-reported outcomes in heart failure with reduced ejection fraction in the era of angiotensin receptor-neprilysin inhibitor therapy

In-Cheol Kim
Jong-Chan Youn
Dong Ryeol Ryu
ResearchOpen Access11 May 2022
Scientific Reports

Volume: 12, P: 1-9
Embryonic stem cell-derived extracellular vesicle-mimetic nanovesicles rescue erectile function by enhancing penile neurovascular regeneration in the streptozotocin-induced diabetic mouse

Mi-Hye Kwon
Kang-Moon Song
Jun-Kyu Suh
ResearchOpen Access27 Dec 2019
Scientific Reports

Volume: 9, P: 1-13
Author Correction: A lignan from Alnus japonica inhibits glioblastoma tumorspheres by suppression of FOXM1

Jin‑Kyoung Shim
Seung Hoon Lim
Seok‑Gu Kang
Amendments and CorrectionsOpen Access30 May 2025
Scientific Reports

Volume: 15, P: 1-4
GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease

In Alzheimer's disease, increased MAOB activity in reactive astrocytes leads to enhanced GABA release, and blockage of this pathway ameliorates memory dysfunction in mouse models.

Seonmi Jo
Oleg Yarishkin
C Justin Lee
Research29 Jun 2014
Nature Medicine

Volume: 20, P: 886-896
Albuminuria, Cerebrovascular Disease and Cortical Atrophy: among Cognitively Normal Elderly Individuals

Eun Bin Cho
Hee-Young Shin
Sang Won Seo
ResearchOpen Access15 Feb 2016
Scientific Reports

Volume: 6, P: 1-8
Sirolimus-coated Eustachian tube balloon dilatation for treating Eustachian tube dysfunction in a rat model

Jeon Min Kang
Song Hee Kim
Jung-Hoon Park
ResearchOpen Access16 Apr 2024
Scientific Reports

Volume: 14, P: 1-10
Author Correction: The power of genetic diversity in genome-wide association studies of lipids

Sarah E. Graham
Shoa L. Clarke
Cristen J. Willer
Amendments and Corrections26 May 2023
Nature

Volume: 618, P: E19-E20
The microbial metabolite imidazole propionate dysregulates bone homeostasis by inhibiting AMP-activated protein kinase (AMPK) signaling

Imidazole propionate, a microbial metabolite, impairs bone homeostasis by inhibiting osteoblast differentiation and enhancing adipocyte differentiation via p38γ activation and AMPK suppression. Metformin counters these effects.

Suk-Gyun Park
Jung-Woo Kim
Jeong-Tae Koh
ResearchOpen Access19 Dec 2024
Communications Biology

Volume: 7, P: 1-12
Author Correction: Automated severity scoring of atopic dermatitis patients by a deep neural network

Chul Hwan Bang
Jae Woong Yoon
Ji Hyun Lee
Amendments and CorrectionsOpen Access27 Jul 2021
Scientific Reports

Volume: 11, P: 1
Engineered Human Ferritin Nanoparticles for Direct Delivery of Tumor Antigens to Lymph Node and Cancer Immunotherapy

Bo-Ram Lee
Ho Kyung Ko
Jeewon Lee
ResearchOpen Access11 Oct 2016
Scientific Reports

Volume: 6, P: 1-12
Drug-coated balloon versus drug-eluting stent for femoropopliteal total occlusions: intraluminal versus subintimal approaches

Yong Hoon Kim
Ae-Young Her
Hyun-Sook Kim
ResearchOpen Access11 Sept 2024
Scientific Reports

Volume: 14, P: 1-11

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