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Advanced filters: Author: Juan Cala-Garcia Clear advanced filters

  • Extracellular matrix (ECM) remodeling is a hallmark of fibrosis thought to be driven by mesenchymal cells. Here, the authors discover that YAP-TEAD/LOX axis is activated in distal lung epithelial cells, which contributes to ECM remodeling in pre-clinical models of pulmonary fibrosis.

    • Darcy Elizabeth Wagner
    • Hani N. Alsafadi
    • Melanie Königshoff
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-20