Despite the absence of frequent mutations of key components of Wnt/β-catenin signalling, this pathway is often constitutively activated in non-small cell lung carcinoma. In this study, the authors demonstrate the inhibitory effect of miR-582-3p on negative regulators of the Wnt/β-catenin pathway which is consequently triggered to sustain lung tumour growth.
- Lishan Fang
- Junchao Cai
- Mengfeng Li
