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Showing 1–3 of 3 results
Advanced filters: Author: Julia P. Schessner Clear advanced filters

  • The spatial mapping of proteins can give important functional insights. Here, Zhu et al. develop a cross-linking mass spectrometry-based spatial proteomics method that does not require protein engineering, affords sub-organelle resolution, and elucidates both protein locations and membrane topologies.

    • Ying Zhu
    • Kerem Can Akkaya
    • Fan Liu
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-18

  • Mass spectrometry-based proteomics faces the challenge of processing vast data amounts. Here, the authors introduce AlphaPept, an open-source, Python-based framework that offers high speed analysis and easy integration for large-scale proteome analysis.

    • Maximilian T. Strauss
    • Isabell Bludau
    • Matthias Mann
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-16

  • Regulated subcellular localization changes control protein function. Here, the authors provide a seamless spatial proteomics pipeline for mapping whole-cell protein localization dynamics, which includes a scalable workflow and a software suite for automated data analysis and visualization.

    • Julia P. Schessner
    • Vincent Albrecht
    • Georg H. H. Borner
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-19