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Showing 1–6 of 6 results
Advanced filters: Author: Julian Gutekunst Clear advanced filters
  • Gutekunst et al. explore the phylogeographic origins of the marbled crayfish, Procambarus virginalis, a parthenogenetic freshwater species. Based on genomic data of the parent species, they demonstrate that both parental haplotypes of P. virginalis were inherited from the Everglades subpopulation of P. fallax.

    • Julian Gutekunst
    • Olena Maiakovska
    • Frank Lyko
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-6
  • DNA demethylation is known to be critical for the development and function of many tissues. Here the authors show that it is also required for intestinal lineage differentiation, and that mice lacking DNA demethylases have altered microbiomes and a predisposition to inflammation.

    • Ihab Ansari
    • Llorenç Solé-Boldo
    • Yehudit Bergman
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-18
  • The marbled crayfish is an emerging invasive species in freshwater habitats. Here, the authors sequence the genome of the marbled crayfish and show that evolution of this decapod crustacean involved genome duplication, triploidy and clonal expansion.

    • Julian Gutekunst
    • Ranja Andriantsoa
    • Frank Lyko
    ResearchOpen Access
    Nature Ecology & Evolution
    Volume: 2, P: 567-573
  • A comparison of DNA methylation patterns between conventionally raised and germ-free mice shows that the presence of a commensal microbiota induces methylation changes at regulatory elements in a subset of genes that are important for intestinal homeostasis.

    • Ihab Ansari
    • Günter Raddatz
    • Yehudit Bergman
    Research
    Nature Microbiology
    Volume: 5, P: 610-619
  • Cutaneous squamous cell carcinoma (cSCC) is a skin cancer that normally progresses from UV-induced actinic keratosis (AK). Here, the authors investigate the epigenomics of cSCC and highlight two distinct subclasses of AK and cSCC originating from distinct keratinocyte differentiation stages.

    • Manuel Rodríguez-Paredes
    • Felix Bormann
    • Frank Lyko
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-9
  • Olena Maiakovska et al. provide whole-genome sequencing of the parthenogenetic and invasive marbled crayfish and develop a computational framework for data analysis of monoclonal genomes. These data and methodology allow the authors to demonstrate genetic separation between two populations and provide the first size estimate for a marbled crayfish colony, which they used to model population growth patterns.

    • Olena Maiakovska
    • Ranja Andriantsoa
    • Frank Lyko
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-7