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Showing 1–1 of 1 results
Advanced filters: Author: Julie Herniman Clear advanced filters
  • Immunostimulatory antibodies have strong potential as anti-cancer therapeutics. Here Elliott et al. show that conformational rigidity determines agonistic activity of antibodies targeting CD40 and 4-1BB and demonstrate further enhancement of agonism through disulfide engineering.

    • Isabel G. Elliott
    • Hayden Fisher
    • Ivo Tews
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13