Postrenal transplant hemolytic uremic syndrome (HUS) can occur as a recurrent orde novodisease. Improved understanding of the mechanisms by which atypical HUS occurs after transplantation should result in the improved management of affected patients. In this Review, Zuber and colleagues discuss recent advances in our understanding of the pathogenesis of atypical HUS and describe diagnostic and therapeutic considerations with regard to renal transplantation in these patients.
- Julien Zuber
- Moglie Le Quintrec
- Christophe Legendre