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Showing 1–10 of 10 results

Advanced filters: Author: Jun Arimoto Clear advanced filters

STAT2 is an essential adaptor in USP18-mediated suppression of type I interferon signaling

STAT2, previously known as a positive effector of interferon signaling, is now shown to participate in negative feedback and suppression of this signaling pathway, by recruiting USP18 to the type I IFN receptor subunit IFNAR2.

Kei-ichiro Arimoto
Sara Löchte
Dong-Er Zhang
Research06 Feb 2017
Nature Structural & Molecular Biology

Volume: 24, P: 279-289
Expansion of interferon inducible gene pool via USP18 inhibition promotes cancer cell pyroptosis

The induction of immunogenic cell death (ICD) can potentiate antitumour immunity. Here the authors show that USP18, a negative regulator of IFN signaling protects cancer cells from ICD by suppressing the expression of canonical and non-canonical IFN-stimulated genes.

Kei-ichiro Arimoto
Sayuri Miyauchi
Dong-Er Zhang
ResearchOpen Access17 Jan 2023
Nature Communications

Volume: 14, P: 1-22
Measurement of nuclear reaction cross sections by using Cherenkov radiation toward high-precision proton therapy

Takamitsu Masuda
Jun Kataoka
Toshiyuki Toshito
ResearchOpen Access07 Feb 2018
Scientific Reports

Volume: 8, P: 1-8
Diagnostic test accuracy of glutamate dehydrogenase for Clostridium difficile: Systematic review and meta-analysis

Jun Arimoto
Nobuyuki Horita
Atsushi Nakajima
ResearchOpen Access15 Jul 2016
Scientific Reports

Volume: 6, P: 1-9
Growth Factor Midkine Aggravates Pulmonary Arterial Hypertension via Surface Nucleolin

Daisuke Kinoshita
Tetsuro Shishido
Masafumi Watanabe
ResearchOpen Access25 Jun 2020
Scientific Reports

Volume: 10, P: 1-14
Blood pressure during long-term cilostazol-based dual antiplatelet therapy after stroke: a post hoc analysis of the CSPS.com trial

Kazunori Toyoda
Masatoshi Koga
Hiroaki Tanaka
ResearchOpen Access09 Jul 2024
Hypertension Research

Volume: 47, P: 2238-2249
Simple and efficient differentiation of human iPSCs into contractible skeletal muscles for muscular disease modeling

Muhammad Irfanur Rashid
Takuji Ito
Yohei Okada
ResearchOpen Access25 May 2023
Scientific Reports

Volume: 13, P: 1-22
Identification and characterization of a novel ISG15-ubiquitin mixed chain and its role in regulating protein homeostasis

Jun-Bao Fan
Kei-lchiro Arimoto
Dong-Er Zhang
ResearchOpen Access30 Jul 2015
Scientific Reports

Volume: 5, P: 1-11
Impact of center volume on in-hospital mortality in adult patients with out‑of‑hospital cardiac arrest resuscitated using extracorporeal cardiopulmonary resuscitation: a secondary analysis of the SAVE-J II study

Kayo Misumi
Yoshihiro Hagiwara
Hideto Yokoi
ResearchOpen Access09 Apr 2024
Scientific Reports

Volume: 14, P: 1-8
Induction of hTERT expression and phosphorylation by estrogen via Akt cascade in human ovarian cancer cell lines

Akiko Kimura
Masahide Ohmichi
Yuji Murata
Research29 Mar 2004
Oncogene

Volume: 23, P: 4505-4515