Silver-catalyzed hydroamidation of siloxy-alkynes is a successful approach for the hydroamidation of internal alkynes, however the mechanism of this reaction is poorly understood. Here, the authors use density functional theory calculations to reveal that the reaction takes place through a silver activated silylium ion migration mediated hydroamidation pathway.
- Heng-Ding Wang
- Ling Jiang
- Hong-Jun Fan
