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Showing 1–3 of 3 results
Advanced filters: Author: Justin M. Reitsma Clear advanced filters
  • SCF ubiquitin ligase-mediated protein turnover is critical for cell function. Here, the authors reveal that CAND2, a CAND1 homolog linked to multiple human diseases, acts as an F-box protein exchange factor, albeit less efficiently than CAND1, to shape SCF assembly and regulate protein degradation.

    • Kankan Wang
    • Lihong Li
    • Xing Liu
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-17
  • A new Burden of Proof meta-analytic method that accounts for between-study heterogeneity and corrects for bias between different study designs is used to interpret the strength of evidence between different pairs of risk factors and health outcomes.

    • Peng Zheng
    • Ashkan Afshin
    • Christopher J. L. Murray
    ResearchOpen Access
    Nature Medicine
    Volume: 28, P: 2038-2044