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Structural basis for fork reversal and RAD51 regulation by the SCF ubiquitin ligase complex of F-box helicase 1

FBH1 is a DNA helicase and ubiquitin ligase that reverses stalled replication forks and limits RAD51 association with chromatin. Here, the authors describe the biochemical requirements for DNA unwinding and fork reversal activities and a cryo-EM structure of the SCF^FBH1 complex bound to a DNA fork.

Briana H. Greer
Javier Mendia-Garcia
Brandt F. Eichman
ResearchOpen Access26 Jan 2026
Nature Communications

P: 1-14
Convergent and divergent evolution of regulatory sites in eukaryotic phosphorylases

Peter K. Hwang
Robert J. Fletterick
Research06 Nov 1986
Nature

Volume: 324, P: 80-84
Earth Oscillations and the Earth's Interior

K. E. BULLEN
R. A. W. HADDON
Research01 Feb 1967
Nature

Volume: 213, P: 574-576
α-Lactalbumin possesses a novel calcium binding loop

D. I. Stuart
K. R. Acharya
D. C. Phillips
Research06 Nov 1986
Nature

Volume: 324, P: 84-87
ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation

Hiroaki Kawasaki
Lou Schiltz
Kazunari K. Yokoyama
Research11 May 2000
Nature

Volume: 405, P: 195-200
Multi-omics in nasal epithelium reveals three axes of dysregulation for asthma risk in the African Diaspora populations

Here, the authors suggest that molecular dysregulation on three axes may play a critical role in asthma within the African Diaspora. RNASeq and DNA methylation data are generated from nasal epithelium including cases and controls from seven different geographic sites.

Brooke Szczesny
Meher Preethi Boorgula
Rasika A. Mathias
ResearchOpen Access28 May 2024
Nature Communications

Volume: 15, P: 1-12
Reduced collagen degradation in pelvic urine precedes kidney fibrosis induced by unilateral ureteral obstruction

Teresa Frattini
Benjamin Breuil
Joost Schanstra
ResearchOpen Access21 Nov 2025
Scientific Reports

Volume: 15, P: 1-9
Creation of Mice Expressing Human Antibody Light Chains by Introduction of a Yeast Artificial Chromosome Containing the Core Region of the Human Immunoglobulin κ Locus

Nicholas P. Davies
Ian R. Rosewell
Marianne Brüggemann
Research01 Aug 1993
Bio/Technology

Volume: 11, P: 911-914
Discovery and characterization of novel small-molecule CXCR4 receptor agonists and antagonists

Rama K. Mishra
Andrew K. Shum
Gary E. Schiltz
ResearchOpen Access26 Jul 2016
Scientific Reports

Volume: 6, P: 1-9
Social needs and hospital readmission in persons living with HIV

Guangjin Zhou
Laura J. Mintz
Siran M. Koroukian
ResearchOpen Access05 Apr 2025
Scientific Reports

Volume: 15, P: 1-10
Histone deacetylase inhibitors are the potent inducer/enhancer of differentiation in acute myeloid leukemia: a new approach to anti-leukemia therapy

H Kosugi
M Towatari
T Naoe
Research09 Sept 1999
Leukemia

Volume: 13, P: 1316-1324
CBP/p300 as a co-factor for the Microphthalmia transcription factor

S Sato
K Roberts
C R Goding
Research26 Jun 1997
Oncogene

Volume: 14, P: 3083-3092
Nucleolin is involved in interferon regulatory factor-2-dependent transcriptional activation

A Masumi
H Fukazawa
K Yamaguchi
Research03 Apr 2006
Oncogene

Volume: 25, P: 5113-5124
HA-MOP knockin mice express the canonical µ-opioid receptor but lack detectable splice variants

Fritzwanker et al. develop a knock-in transgenic mouse line in which the hemagglutinin epitope tag sequence is fused with the amino-terminus of the µ-opioid receptor. Their model enables more efficient immunodetection of G protein-coupled receptors.

Sebastian Fritzwanker
Lionel Moulédous
Andrea Kliewer
ResearchOpen Access14 Sept 2021
Communications Biology

Volume: 4, P: 1-10
δ-(L-α-Aminoadipyl)-L-Cysteinyl-D-Valine Synthetase, the Multienzyme Integrating the Four Primary Reactions in β-Lactam Biosynthesis, as a Model Peptide Synthetase

Yair Aharonowitz
Jürgen Bergmeyer
Jinyou Zhang
Reviews01 Jul 1993
Bio/Technology

Volume: 11, P: 807-810
Mecamylamine Attenuates Cue-Induced Reinstatement of Nicotine-Seeking Behavior in Rats

Xiu Liu
Anthony R Caggiula
Russell E Poland
Research21 Jun 2006
Neuropsychopharmacology

Volume: 32, P: 710-718
Gray matter anomalies in pedophiles with and without a history of child sexual offending

B Schiffer
T Amelung
H Walter
ResearchOpen Access16 May 2017
Translational Psychiatry

Volume: 7, P: e1129
Male offspring production by asexual Potamopyrgus antipodarum, a New Zealand snail

M Neiman
K Larkin
P Wilton
Research11 Apr 2012
Heredity

Volume: 109, P: 57-62
Elevated S100B levels in schizophrenia are associated with insulin resistance

J Steiner
M Walter
B Bogerts
Correspondence22 Dec 2009
Molecular Psychiatry

Volume: 15, P: 3-4

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Structural basis for fork reversal and RAD51 regulation by the SCF ubiquitin ligase complex of F-box helicase 1

Convergent and divergent evolution of regulatory sites in eukaryotic phosphorylases

Earth Oscillations and the Earth's Interior

α-Lactalbumin possesses a novel calcium binding loop

ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation

Multi-omics in nasal epithelium reveals three axes of dysregulation for asthma risk in the African Diaspora populations

Reduced collagen degradation in pelvic urine precedes kidney fibrosis induced by unilateral ureteral obstruction

Creation of Mice Expressing Human Antibody Light Chains by Introduction of a Yeast Artificial Chromosome Containing the Core Region of the Human Immunoglobulin κ Locus

Discovery and characterization of novel small-molecule CXCR4 receptor agonists and antagonists

Social needs and hospital readmission in persons living with HIV

Histone deacetylase inhibitors are the potent inducer/enhancer of differentiation in acute myeloid leukemia: a new approach to anti-leukemia therapy

CBP/p300 as a co-factor for the Microphthalmia transcription factor

Nucleolin is involved in interferon regulatory factor-2-dependent transcriptional activation

HA-MOP knockin mice express the canonical µ-opioid receptor but lack detectable splice variants

δ-(L-α-Aminoadipyl)-L-Cysteinyl-D-Valine Synthetase, the Multienzyme Integrating the Four Primary Reactions in β-Lactam Biosynthesis, as a Model Peptide Synthetase

Mecamylamine Attenuates Cue-Induced Reinstatement of Nicotine-Seeking Behavior in Rats

Gray matter anomalies in pedophiles with and without a history of child sexual offending

Male offspring production by asexual Potamopyrgus antipodarum, a New Zealand snail

Elevated S100B levels in schizophrenia are associated with insulin resistance

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