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Advanced filters: Author: Kalipada Pahan Clear advanced filters

Selective targeting of the TLR2/MyD88/NF-κB pathway reduces α-synuclein spreading in vitro and in vivo

The mechanisms underlying the spreading of α-synuclein in various α-synucleinopathies are unclear. Here, the authors show that targeting the TLR2/MyD88/NF-κB pathway can reduce α-synuclein spreading, reduce neuroinflammation, and protect dopaminergic neurons in vitro and in mouse models

Debashis Dutta
Malabendu Jana
Kalipada Pahan
ResearchOpen Access10 Sept 2021
Nature Communications

Volume: 12, P: 1-19
Modulation of Endogenous Antioxidant Enzymes by Nitric Oxide in Rat C6 Glial Cells † 1722

Kazushige Dobashi
Kalipada Pahan
Inderjit Singh
Research01 Apr 1997
Pediatric Research

Volume: 41, P: 289
Identification and characterization of PPARα ligands in the hippocampus

Three endogenous ligands of the nuclear receptor PPARα—hydroxydimethylbutyrate, hexadecanamide, and octadecenamide—are potentially responsible for noncanonical activity of PPARα in synaptic function and hippocampal plasticity.

Avik Roy
Madhuchhanda Kundu
Kalipada Pahan
Research17 Oct 2016
Nature Chemical Biology

Volume: 12, P: 1075-1083
BPOZ-2 Gene Delivery Ameliorates Alpha-Synucleinopathy in A53T Transgenic Mouse Model of Parkinson’s Disease

Avik Roy
Suresh Babu Rangasamy
Kalipada Pahan
ResearchOpen Access26 Feb 2016
Scientific Reports

Volume: 6, P: 1-14

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