The authors synthesized formalin-fixed paraffin-embedded (FFPE)-like images (“virtual FFPE”) from frozen (FF) section samples. Five board-certified pathologists evaluated the results in a blinded test. Clinical assessments of disease on the virtual FFPE images showed a higher inter-observer agreement compared to FF images. These findings suggest that virtual FFPE images can increase the quality and speed of histopathologic examinations without adding to cost or effort.
- Kianoush Falahkheirkhah
- Tao Guo
- Rohit Bhargava