Through transcriptional and phenotypic profiling, authors show that ribose catabolism by the fungus Candida albicans shapes the metabolic landscape of the intra-abdominal cavity to derepress agr signaling in the bacterium Staphylococcus aureus, driving α-toxin release and synergistic lethality during co-infection.
- Saikat Paul
- Olivia A. Todd
- Brian M. Peters