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Advanced filters: Author: Karel Otero Clear advanced filters

A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity

This study identifies a subset of natural killer (NK) cells in the gut that produce interleukin-22, rather than mediate target cell killing. It is suggested that these NK cells, referred to as NK-22 cells, may help constrain inflammation and contribute to the maintenance of mucosal integrity.

Marina Cella
Anja Fuchs
Marco Colonna
Research02 Nov 2008
Nature

Volume: 457, P: 722-725
Macrophage colony-stimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and β-catenin

Macrophage colony-stimulating factor (M-CSF) induces the proliferation of mononuclear phagocytes, and DAP12 is needed for their function. Colonna and colleagues show that DAP12 is also needed for M-CSF-induced stabilization of β-catenin.

Karel Otero
Isaiah R Turnbull
Marco Colonna
Research07 Jun 2009
Nature Immunology

Volume: 10, P: 734-743

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A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity

Macrophage colony-stimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and β-catenin

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