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Showing 1–3 of 3 results
Advanced filters: Author: Karl Gatterdam Clear advanced filters

  • Cyclin-dependent kinase 7 (Cdk7) is required in cell-cycle and transcriptional regulation. It is regulated by two phosphorylations in the activation segment. Here, the authors report a structure of the human Cdk7/Cyclin H/Mat1 complex containing both phosphorylations, with further insights into the regulatory mechanisms.

    • Robert Düster
    • Kanchan Anand
    • Matthias Geyer
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-15

  • Brüchert et al. describe the application of high-affinity super-chelator probes that are linked to a fluorophore for the detection of His-tagged proteins using PAGE. Their system has the advantage over conventional antibody staining in the ease of application and ultra-sensitive detection.

    • Stefan Brüchert
    • Eike F. Joest
    • Robert Tampé
    ResearchOpen Access
    Communications Biology
    Volume: 3, P: 1-7