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Advanced filters: Author: Karolien Grauwen Clear advanced filters

  • NLRP3 is a critical intracellular inflammasome sensor and an important clinical target against inflammation-driven human diseases. Here, the authors determined Cryo-EM structures of human NLRP3 in its closed and open states, elucidating the mechanism of NLRP3 inflammasome activation.

    • Xiaodi Yu
    • Rosalie E. Matico
    • Sujata Sharma
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-13