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HIV vaccine candidate activation of hypoxia and the inflammasome in CD14⁺ monocytes is associated with a decreased risk of SIV_mac251 acquisition

Distinct monocyte subsets associate with different outcomes of SIV vaccines.

Monica Vaccari
Slim Fourati
Genoveffa Franchini
Research21 May 2018
Nature Medicine

Volume: 24, P: 847-856
Inter-organ signalling by HRG-7 promotes systemic haem homeostasis

Sinclair et al. show in Caenorhabditis elegans that intestinal HRG-7 communicates haem status with extra-intestinal tissues. Reciprocally, a DBL-1-dependent signal from neurons regulates both hrg-7 and haem transport.

Jason Sinclair
Katherine Pinter
Iqbal Hamza
Research05 Jun 2017
Nature Cell Biology

Volume: 19, P: 799-807

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HIV vaccine candidate activation of hypoxia and the inflammasome in CD14+ monocytes is associated with a decreased risk of SIVmac251 acquisition

Inter-organ signalling by HRG-7 promotes systemic haem homeostasis

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HIV vaccine candidate activation of hypoxia and the inflammasome in CD14⁺ monocytes is associated with a decreased risk of SIV_mac251 acquisition