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Showing 1–2 of 2 results
Advanced filters: Author: Katie Loi Clear advanced filters

  • A novel antiviral targeting the SARS-CoV-2 PLpro protease shows strong efficacy in a mouse model, preventing lung pathology and reducing brain dysfunction. The study provides proof-of-principle that PLpro inhibition may be a viable strategy for preventing and treating long COVID.

    • Stefanie M. Bader
    • Dale J. Calleja
    • David Komander
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-20

  • RNA sequencing data and tumour pathology observations of non-small-cell lung cancers indicate that the immune cell microenvironment exerts strong evolutionary selection pressures that shape the immune-evasion capacity of tumours.

    • Rachel Rosenthal
    • Elizabeth Larose Cadieux
    • Andrew Kidd
    Research
    Nature
    Volume: 567, P: 479-485