Nature Search

A potent neutralizing antibody with therapeutic potential against all four serotypes of dengue virus

Meihui Xu
Roland Zuest
Katja Fink
ResearchOpen Access23 Jan 2017
npj Vaccines

Volume: 2, P: 1-10
Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody

The monoclonal antibody S309, identified from memory B cells of an individual infected with SARS-CoV in 2003, or antibody cocktails that contain this antibody potently neutralize SARS-CoV-2.

Dora Pinto
Young-Jun Park
Davide Corti
Research18 May 2020
Nature

Volume: 583, P: 290-295
Genomic investigations of unexplained acute hepatitis in children

An investigation using various methods reports an association between adeno-associated virus 2 and paediatric hepatitis of unknown aetiology.

Sofia Morfopoulou
Sarah Buddle
Judith Breuer
ResearchOpen Access30 Mar 2023
Nature

Volume: 617, P: 564-573
Diminishing benefits of urban living for children and adolescents’ growth and development

The advantage of living in cities compared with rural areas with respect to height and BMI in children and adolescents has generally become smaller globally from 1990 to 2020, except in sub-Saharan Africa.

Anu Mishra
Bin Zhou
Majid Ezzati
ResearchOpen Access29 Mar 2023
Nature

Volume: 615, P: 874-883
Design of fast proteolysis-based signaling and logic circuits in mammalian cells

Protease-cleavable orthogonal-coiled-coil-based (SPOC) systems, in which split viral proteases are activated by small molecules and cleave coiled-coil protease substrates, reprogram signaling with rapid kinetics in mammalian cells.

Tina Fink
Jan Lonzarić
Roman Jerala
Research10 Dec 2018
Nature Chemical Biology

Volume: 15, P: 115-122
Exploring beyond clinical routine SARS-CoV-2 serology using MultiCoV-Ab to evaluate endemic coronavirus cross-reactivity

Serology is an important way to monitor SARS-CoV-2 infection in the population and support vaccine development. Here the authors develop a multiplex immunoassay including spike and nucleocapsid proteins of SARS-CoV-2 and the endemic human coronaviruses with high specificity and sensitivity.

Matthias Becker
Monika Strengert
Nicole Schneiderhan-Marra
ResearchOpen Access19 Feb 2021
Nature Communications

Volume: 12, P: 1-12
Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation

DNA double-strand breaks in ribosomal DNA repeats is associated with repression of ribosomal RNA synthesis. Here the authors reveal a cooperation between TOPBP1 and Treacle in the signaling cascade that triggers transcriptional inhibition and nucleolar segregation in response to rDNA breaks.

Clémence Mooser
Ioanna-Eleni Symeonidou
Manuel Stucki
ResearchOpen Access08 Jan 2020
Nature Communications

Volume: 11, P: 1-16
Differences in the mechanisms of growth control in contact-inhibited and serum-deprived human fibroblasts

Cornelia Dietrich
Katja Wallenfang
Raimund Wieser
Research27 Nov 1997
Oncogene

Volume: 15, P: 2743-2747
Deliberate removal of T cell help improves virus-neutralizing antibody production

Mike Recher
Karl S Lang
Rolf M Zinkernagel
Research08 Aug 2004
Nature Immunology

Volume: 5, P: 934-942
Extralymphatic virus sanctuaries as a consequence of potent T-cell activation

Mike Recher
Karl S Lang
Rolf M Zinkernagel
Research04 Nov 2007
Nature Medicine

Volume: 13, P: 1316-1323
Publisher Correction: A potent neutralizing antibody with therapeutic potential against all four serotypes of dengue virus

Meihui Xu
Roland Zuest
Katja Fink
Amendments and CorrectionsOpen Access01 Feb 2018
npj Vaccines

Volume: 3, P: 1
Skin dendritic cell and T cell activation associated with dengue shock syndrome

Huynh Thi Le Duyen
Daniela Cerny
Katja Fink
ResearchOpen Access27 Oct 2017
Scientific Reports

Volume: 7, P: 1-12
TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection

TOX is a critical factor for the normal progression of T cell dysfunction and the maintenance of exhausted T cells during chronic infections.

Francesca Alfei
Kristiyan Kanev
Dietmar Zehn
Research17 Jun 2019
Nature

Volume: 571, P: 265-269
Differential Effects of Caspase-1/Interleukin-1β–Converting Enzyme on Acinar Cell Necrosis and Apoptosis in Severe Acute Experimental Pancreatitis

Bettina Rau
Adam Paszkowski
Hans G Beger
Research01 Jul 2001
Laboratory Investigation

Volume: 81, P: 1001-1013
Publisher Correction: The dengue-specific immune response and antibody identification with machine learning

Eriberto Noel Natali
Alexander Horst
Enkelejda Miho
Amendments and CorrectionsOpen Access09 Dec 2024
npj Vaccines

Volume: 9, P: 1
Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells

Lymph nodes help clear infecting pathogens and prevent their dissemination. In the case of lymph-borne virus, this involves a particular subpopulation of macrophages that is shown to capture the viral particles and present them to B cells, leading to B cell activation.

Tobias Junt
E. Ashley Moseman
Ulrich H. von Andrian
Research14 Oct 2007
Nature

Volume: 450, P: 110-114
A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population

Fergus Couch and colleagues report a genome-wide association study for modifiers of breast cancer susceptibility in BRCA1 mutation carriers. They identify a locus at 19p13 associated with breast cancer risk in BRCA1 mutation carriers, and further replication studies identify this locus as associated with estrogen receptor–negative breast cancer in the general population.

Antonis C Antoniou
Xianshu Wang
Fergus J Couch
Research19 Sept 2010
Nature Genetics

Volume: 42, P: 885-892
Author Correction: The dengue-specific immune response and antibody identification with machine learning

Eriberto Noel Natali
Alexander Horst
Enkelejda Miho
Amendments and CorrectionsOpen Access13 Feb 2024
npj Vaccines

Volume: 9, P: 1
A perspective on potential antibody-dependent enhancement of SARS-CoV-2

The antibody-dependent enhancement of disease is reviewed, with an emphasis on implications for the prevention and treatment of SARS-CoV-2 infection.

Ann M. Arvin
Katja Fink
Herbert W. Virgin
Reviews13 Jul 2020
Nature

Volume: 584, P: 353-363
The dengue-specific immune response and antibody identification with machine learning

Eriberto Noel Natali
Alexander Horst
Enkelejda Miho
ResearchOpen Access20 Jan 2024
npj Vaccines

Volume: 9, P: 1-15
Author Correction: Mimicking immune signatures of flavivirus infection with targeted adjuvants improves dengue subunit vaccine immunogenicity

Katell Bidet
Victor Ho
Jianzhu Chen
Amendments and CorrectionsOpen Access24 Oct 2019
npj Vaccines

Volume: 4, P: 1
Single molecule, near full-length genome sequencing of dengue virus

Thiruni N. Adikari
Nasir Riaz
Chaturaka Rodrigo
ResearchOpen Access23 Oct 2020
Scientific Reports

Volume: 10, P: 1-12
Mimicking immune signatures of flavivirus infection with targeted adjuvants improves dengue subunit vaccine immunogenicity

Katell Bidet
Victor Ho
Jianzhu Chen
ResearchOpen Access25 Jun 2019
npj Vaccines

Volume: 4, P: 1-13

Search

A potent neutralizing antibody with therapeutic potential against all four serotypes of dengue virus

Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody

Genomic investigations of unexplained acute hepatitis in children

Diminishing benefits of urban living for children and adolescents’ growth and development

Design of fast proteolysis-based signaling and logic circuits in mammalian cells

Exploring beyond clinical routine SARS-CoV-2 serology using MultiCoV-Ab to evaluate endemic coronavirus cross-reactivity

Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation

Differences in the mechanisms of growth control in contact-inhibited and serum-deprived human fibroblasts

Deliberate removal of T cell help improves virus-neutralizing antibody production

Extralymphatic virus sanctuaries as a consequence of potent T-cell activation

Publisher Correction: A potent neutralizing antibody with therapeutic potential against all four serotypes of dengue virus

Skin dendritic cell and T cell activation associated with dengue shock syndrome

TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection

Differential Effects of Caspase-1/Interleukin-1β–Converting Enzyme on Acinar Cell Necrosis and Apoptosis in Severe Acute Experimental Pancreatitis

Publisher Correction: The dengue-specific immune response and antibody identification with machine learning

Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population

Author Correction: The dengue-specific immune response and antibody identification with machine learning

A perspective on potential antibody-dependent enhancement of SARS-CoV-2

The dengue-specific immune response and antibody identification with machine learning

Author Correction: Mimicking immune signatures of flavivirus infection with targeted adjuvants improves dengue subunit vaccine immunogenicity

Single molecule, near full-length genome sequencing of dengue virus

Mimicking immune signatures of flavivirus infection with targeted adjuvants improves dengue subunit vaccine immunogenicity

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