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Advanced filters: Author: Kay Eckelt Clear advanced filters

  • Alloswitch-1 is a photoswitchable modulator for mGlu5, and it is the first photoswitchable allosteric GPCR modulator. It was generated by adding the azobenzene Ar-N=N-Ar scaffold into an existing positive allosteric modulator of the receptor.

    • Silvia Pittolo
    • Xavier Gómez-Santacana
    • Pau Gorostiza
    Research
    Nature Chemical Biology
    Volume: 10, P: 813-815