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Showing 1–3 of 3 results
Advanced filters: Author: Kayoko Sugita Clear advanced filters

  • Naturally occurring peptides with high membrane permeability often have backbone ester bonds. Here, the authors investigated the effect of an amide-to-ester substitution on membrane permeability of peptides and found the substitution is useful for improving membrane permeability of cyclic peptides.

    • Yuki Hosono
    • Satoshi Uchida
    • Shinsuke Sando
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-14

  • Transplants of consortia with limited numbers of strains of commensal bacteria derived from healthy human stool samples are able to suppress intestinal Enterobacteriaceae by regulating gluconate availability, suggesting potential therapies for infectious and inflammatory diseases.

    • Munehiro Furuichi
    • Takaaki Kawaguchi
    • Kenya Honda
    ResearchOpen Access
    Nature
    Volume: 633, P: 878-886

  • A consortium of 11 bacterial strains from the healthy human gut microbiota can strongly induce interferon-γ-producing CD8 T cells in the intestine, and enhance both resistance to bacterial infection and the therapeutic efficacy of immune checkpoint inhibitors.

    • Takeshi Tanoue
    • Satoru Morita
    • Kenya Honda
    Research
    Nature
    Volume: 565, P: 600-605