ortho-Quinone methides are highly reactive transient intermediates found in some organic syntheses and biological processes. The generation of these species often requires pre-functionalized substrates and/or metal oxidants, but now the chemoselective oxidative generation of ortho-quinone methides from ortho-alkylarenols has been achieved using hypoiodite catalysis under nearly neutral conditions.
- Muhammet Uyanik
- Kohei Nishioka
- Kazuaki Ishihara
