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Cosmic kidney disease: an integrated pan-omic, physiological and morphological study into spaceflight-induced renal dysfunction

Siew et al. using multi-omic, physiological & imaging approaches have demonstrated that spaceflight causes kidney remodelling, suggesting a contribution to kidney stone formation, & that space radiation causes kidney damage & early signs of dysfunction.

Keith Siew
Kevin A. Nestler
Stephen B. Walsh
ResearchOpen Access11 Jun 2024
Nature Communications

Volume: 15, P: 1-20
Association between pathologic response and survival after neoadjuvant therapy in lung cancer

Analysis of the phase 3 CheckMate 816 trial shows that the depth of pathologic response as assessed by percent residual viable tumor is correlated with event-free survival following neoadjuvant immunotherapy plus chemotherapy, supporting pathologic response as a biomarker of survival.

Julie Stein Deutsch
Ashley Cimino-Mathews
Janis M. Taube
ResearchOpen Access30 Oct 2023
Nature Medicine

Volume: 30, P: 218-228
Adiponectin gene ADIPOQ SNP associations with serum adiponectin in two female populations and effects of SNPs on promoter activity

Theodosios Kyriakou
Laura J. Collins
Sandra D. O’Dell
Research01 Aug 2008
Journal of Human Genetics

Volume: 53, P: 718-727

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