In this Opinion article, Buchheitet al. describe the cellular changes that regulate cell viability when cells become detached from the ECM. In particular, they discuss how cancer cells take advantage of these specific processes and how better understanding them will be instrumental in designing therapeutic strategies that aim to eliminate ECM-detached metastatic cells.
- Cassandra L. Buchheit
- Kelsey J. Weigel
- Zachary T. Schafer
