Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–5 of 5 results
Advanced filters: Author: Ken Coppieters Clear advanced filters

  • Adaptor for IL-17 receptors (Act1) is known to be crucial for IL-17-mediated immune responses. Here the authors show that Act1 also functions as a negative regulator of T and B cells by direct inhibition of STAT3.

    • Cun-Jin Zhang
    • Chenhui Wang
    • Xiaoxia Li
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-14

  • It is unknown how T cell antigen receptors from autoreactive CD8+ T cells recognize self. A new paper shows that an unorthodox, low-affinity way of interacting with targets may be at the basis of autoimmunity.

    • Ken T Coppieters
    • Matthias G von Herrath
    News & Views
    Nature Immunology
    Volume: 13, P: 205-206

  • The cell-selective permeability of a retrievable microporous device encapsulating human therapeutic cells and implanted in the intraperitoneal space of mice provides long-term protection to the transplanted cells by dampening foreign-body responses and preventing the immune rejection of the graft.

    • Ken Coppieters
    • Louise Winkel
    • Matthias von Herrath
    News & Views
    Nature Biomedical Engineering
    Volume: 4, P: 763-764

  • Most of the more than 200 known genetic risk loci for inflammatory bowel disease (IBD) reside in regulatory regions. Here, the authors provide eQTL datasets for six circulating immune cell types and ileal, colonic and rectal biopsies to map regulatory modules and identify potential causative genes for IBD.

    • Yukihide Momozawa
    • Julia Dmitrieva
    • Michel Georges
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-18