The plant hormone abscisic acid (ABA) is a regulator of plant growth, development and responses to environmental stresses. Within plants, the PYR/PYL/RCAR family of START proteins receives ABA to inhibit the phosphatase activity of the group-A protein phophatases 2C (PP2Cs). Here, the crystal structures of ABA bound to its receptor PYL1 and a complex formed between ABA, PYL1 and the PP2C protein ABI1 are presented, shedding light on the structural basis of ABA signalling.
- Ken-ichi Miyazono
- Takuya Miyakawa
- Masaru Tanokura
