Inhaled allergens induce many changes in airway function. Kheradmand and colleagues show that matrix metalloproteinase 7 activates the cytokine interleukin 25 and inhibits retinoic acid–mediated induction of regulatory T cells, thereby heightening allergic responses.
- Sangeeta Goswami
- Pornpimon Angkasekwinai
- Farrah Kheradmand