Nature Search

Renal Damage in the SHR/N-cp Type 2 Diabetes Model: Comparison of an Angiotensin-Converting Enzyme Inhibitor and Endothelin Receptor Blocker

Marie-Luise Gross
Eberhard Ritz
Kerstin Amann
Research01 Sept 2003
Laboratory Investigation

Volume: 83, P: 1267-1277
Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury

Necroptosis, a form of cell death, occurs in acute renal injury. Here, the authors show that ferroptosis—a form of cell death dependent on iron - also occurs during acute kidney injury, and show that an inhibitor of ferroptosis can improve survival in a mouse model of acute kidney damage.

Wulf Tonnus
Claudia Meyer
Andreas Linkermann
ResearchOpen Access20 Jul 2021
Nature Communications

Volume: 12, P: 1-14
The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis

Bortezomib, a drug useful for the treatment of multiple myeloma, reduces kidney damage in animal models of lupus.

Kirsten Neubert
Silke Meister
Reinhard E Voll
Research08 Jun 2008
Nature Medicine

Volume: 14, P: 748-755
Amyloid fibril structure from the vascular variant of systemic AA amyloidosis

This study reports the cryo-EM structures of AA amyloid fibrils from two patients with vascular AA amyloidosis. The findings imply that different disease variants in systemic amyloidosis are associated with different fibril structures.

Sambhasan Banerjee
Julian Baur
Marcus Fändrich
ResearchOpen Access25 Nov 2022
Nature Communications

Volume: 13, P: 1-8
Structured illumination microscopy and automatized image processing as a rapid diagnostic tool for podocyte effacement

Florian Siegerist
Silvia Ribback
Nicole Endlich
ResearchOpen Access13 Sept 2017
Scientific Reports

Volume: 7, P: 1-11
Crosstalk of injured podocytes with parietal epithelial cells through Wnt4/β-Catenin signaling

Eike Schwartze
Eva Pfister
Christoph Daniel
ResearchOpen Access04 Jun 2025
Scientific Reports

Volume: 15, P: 1-15
Zyxin is important for the stability and function of podocytes, especially during mechanical stretch

This study highlights the essential role of zyxin for podocytes. Zyxin loss in vitro reduced the expression of vinculin, VASP and matrix proteins. In mice, the knockout of zyxin resulted in proteinuria and effacement of podocyte foot processes.

Felix Kliewe
Florian Siegerist
Nicole Endlich
ResearchOpen Access11 Apr 2024
Communications Biology

Volume: 7, P: 1-14
Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis

Claudia Günther
Eva Martini
Christoph Becker
Research14 Sept 2011
Nature

Volume: 477, P: 335-339
FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair

Friedhelm Hildebrandt, Agata Smogorzewska and colleagues show that mutations in the DNA repair gene FAN1 cause karyomegalic interstitial nephritis. These findings implicate deficient DNA damage response signaling in the pathophysiology of renal fibrosis.

Weibin Zhou
Edgar A Otto
Friedhelm Hildebrandt
Research08 Jul 2012
Nature Genetics

Volume: 44, P: 910-915
Mesenchymal stem cells correct haemodynamic dysfunction associated with liver injury after extended resection in a pig model

Hans-Michael Tautenhahn
Sandra Brückner
Bruno Christ
ResearchOpen Access01 Jun 2017
Scientific Reports

Volume: 7, P: 1-13
Mig6 is a negative regulator of EGF receptor–mediated skin morphogenesis and tumor formation

Ingvar Ferby
Markus Reschke
Rüdiger Klein
Research30 Apr 2006
Nature Medicine

Volume: 12, P: 568-573
Renal effects of the serine protease inhibitor aprotinin in healthy conscious mice

Stefan Wörner
Bernhard N. Bohnert
Ferruh Artunc
ResearchOpen Access23 Mar 2021
Acta Pharmacologica Sinica

Volume: 43, P: 111-120
Cellular stress induces erythrocyte assembly on intravascular von Willebrand factor strings and promotes microangiopathy

Jan P. Nicolay
Verena Thorn
Stefan W. Schneider
ResearchOpen Access19 Jul 2018
Scientific Reports

Volume: 8, P: 1-15
Studying the role of fascin-1 in mechanically stressed podocytes

Felix Kliewe
Christian Scharf
Nicole Endlich
ResearchOpen Access30 Aug 2017
Scientific Reports

Volume: 7, P: 1-14
G Protein-coupled Estrogen Receptor Protects from Atherosclerosis

Matthias R. Meyer
Natalie C. Fredette
Eric R. Prossnitz
ResearchOpen Access23 Dec 2014
Scientific Reports

Volume: 4, P: 1-9
Comparison of different normalization strategies for the analysis of glomerular microRNAs in IgA nephropathy

Clemens L. Bockmeyer
Karen Säuberlich
Jan U. Becker
ResearchOpen Access24 Aug 2016
Scientific Reports

Volume: 6, P: 1-14
Impairment of podocyte function by diphtheria toxin—a new reversible proteinuria model in mice

Andreas Goldwich
Alexander Steinkasserer
Kerstin Amann
Research24 Sept 2012
Laboratory Investigation

Volume: 92, P: 1674-1685
Renoprotective effect of a dopamine D3 receptor antagonist in experimental type II diabetes

Marie-Luise P Gross
Andreas Koch
Eberhard Ritz
Research09 Jan 2006
Laboratory Investigation

Volume: 86, P: 262-274

Search

Renal Damage in the SHR/N-cp Type 2 Diabetes Model: Comparison of an Angiotensin-Converting Enzyme Inhibitor and Endothelin Receptor Blocker

Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury

The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis

Amyloid fibril structure from the vascular variant of systemic AA amyloidosis

Structured illumination microscopy and automatized image processing as a rapid diagnostic tool for podocyte effacement

Crosstalk of injured podocytes with parietal epithelial cells through Wnt4/β-Catenin signaling

Zyxin is important for the stability and function of podocytes, especially during mechanical stretch

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis

FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair

Mesenchymal stem cells correct haemodynamic dysfunction associated with liver injury after extended resection in a pig model

Mig6 is a negative regulator of EGF receptor–mediated skin morphogenesis and tumor formation

Renal effects of the serine protease inhibitor aprotinin in healthy conscious mice

Cellular stress induces erythrocyte assembly on intravascular von Willebrand factor strings and promotes microangiopathy

Studying the role of fascin-1 in mechanically stressed podocytes

G Protein-coupled Estrogen Receptor Protects from Atherosclerosis

Comparison of different normalization strategies for the analysis of glomerular microRNAs in IgA nephropathy

Impairment of podocyte function by diphtheria toxin—a new reversible proteinuria model in mice

Renoprotective effect of a dopamine D3 receptor antagonist in experimental type II diabetes

Search

Quick links

Search

Filter By:

Search

Quick links