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Showing 1–4 of 4 results

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COMPARISON OF THE VIRUS-RECEPTOR INTERACTIONS OF HUMAN PARAINFLUENZA VIRUSES TYPES 1, 2 and 3. † 995

Elizabeth Carlin
Kety Huberman
Anne Moscona
Research01 Apr 1996
Pediatric Research

Volume: 39, P: 168
Immunogenic neoantigens derived from gene fusions stimulate T cell responses

Fusion proteins in cancers with low mutational burden represent functional neoantigens that elicit T cell activation and mediate responses to immunotherapy.

Wei Yang
Ken-Wing Lee
Luc G. T. Morris
Research22 Apr 2019
Nature Medicine

Volume: 25, P: 767-775
PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors

Ping Chi and colleagues identify recurrent inactivating mutations in the PRC2 core components EED and SUZ12 in malignant peripheral nerve sheath tumors. They further show that PRC2 loss is associated with loss of H3K27 trimethylation and aberrant expression of PRC2 target genes and downstream pathways.

William Lee
Sewit Teckie
Ping Chi
Research21 Sept 2014
Nature Genetics

Volume: 46, P: 1227-1232
The mutational landscape of adenoid cystic carcinoma

Timothy Chan and colleagues report exome and genome sequencing of 60 adenoid cystic carcinoma (ACC) tumor-normal pairs. They identify multiple pathways recurrently disrupted in ACC and provide evidence that KDM6A and PIK3CA are functionally relevant candidate ACC driver genes.

Allen S Ho
Kasthuri Kannan
Timothy A Chan
Research19 May 2013
Nature Genetics

Volume: 45, P: 791-798

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