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Showing 1–3 of 3 results
Advanced filters: Author: Kevin M. Meighen-Berger Clear advanced filters

  • Membrane proteins are essential for any cell but difficult to fold. Here, the authors show that the EMC acts as a chaperone for membrane proteins. They dissect client recognition and provide a molecular mechanism that underlies this EMC function.

    • Carolin J. Klose
    • Kevin M. Meighen-Berger
    • Matthias J. Feige
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16

  • A fundamental step in membrane protein biogenesis is their integration into the lipid bilayer with a defined orientation of each transmembrane segment. Here, the authors show that mutations in connexin 32 can cause failures in membrane integration which is detected by the ER chaperone machinery.

    • João P. L. Coelho
    • Matthias Stahl
    • Matthias J. Feige
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-10