Mitral regurgitation (MR) can fluctuate physiologically in response to various stimuli such as exercise and ischaemia. This dynamic behaviour might also have prognostic value, as a marked increase in regurgitant volume or systolic pulmonary artery pressure is indicative of lower symptom-free survival. In this Review, Lancellotti et al. discuss the optimal treatment strategy for patients with dynamic MR, which include mitral valve surgery, cardiac resynchronization therapy, and new mitral valve approaches.
- Patrizio Lancellotti
- Khalil Fattouch
- Giovanni La Canna
