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Advanced filters: Author: Kira E Böhmer Clear advanced filters

  • A new bacterial toxin from pathogen Photorhabdus asymbiotica is now described. The toxin contains a domain with glycosyltransferase activity that modifies a tyrosine residue of Rho GTPases in the host cell, inhibiting Rho activation and interaction with downstream effectors. The second domain is a glutamine deamidase that blocks GTP hydrolysis by Gaq/11 and Gai proteins.

    • Thomas Jank
    • Xenia Bogdanović
    • Klaus Aktories
    Research
    Nature Structural & Molecular Biology
    Volume: 20, P: 1273-1280