Nature Search

Milestone in predicting core plasma turbulence: successful multi-channel validation of the gyrokinetic code GENE

Plasma turbulence is the main driver to deteriorate the performance of fusion power plants. This work presents an unprecedented comparison of plasma turbulence between experiment and simulation, proving that the gyrokinetic model GENE reached a high level of maturity to predict core turbulence.

Klara Höfler
Tobias Görler
S. Zoletnik
ResearchOpen Access15 Mar 2025
Nature Communications

Volume: 16, P: 1-11
Real-world analysis of immune checkpoint inhibitor efficacy and response predictors in patients treated at the CCCMunich^LMU outpatient clinic

Klara Dorman
Kilian Breitenwieser
Anna Reischer
ResearchOpen Access08 Dec 2025
Scientific Reports

Volume: 15, P: 1-11
Simultaneous targeting of KRAS and CDK4 synergistically induces durable growth arrest in pancreatic cancer cells

Maj-Britt Paulsohn
Klara Henrike Frahnert
Matthias Dobbelstein
ResearchOpen Access23 Dec 2025
Cell Death & Disease

Volume: 17, P: 1-22
The hypolipidemic effect of MI-883, the combined CAR agonist/ PXR antagonist, in diet-induced hypercholesterolemia model

CAR and PXR receptors are known to regulate metabolism, however, there is no dual human ligand suitable for therapy. Here, the authors show a CAR agonist/PXR antagonist, MI-883, which regulates cholesterol/bile acid homeostasis by leveraging CAR and PXR activations in plasma cholesterol regulation.

Jan Dusek
Ivana Mejdrová
Petr Pavek
ResearchOpen Access06 Feb 2025
Nature Communications

Volume: 16, P: 1-21
An LKB1–mitochondria axis controls T_H17 effector function

OPA1 regulates the formation of the distinct mitochondrial morphology observed in T helper 17 cells, which influences cytokine expression via LKB1.

Francesc Baixauli
Klara Piletic
Erika L. Pearce
Research28 Sept 2022
Nature

Volume: 610, P: 555-561
Progress towards sustainable agriculture hampered by siloed scientific discourses

Two major discourses for agricultural sustainability, agroecology and sustainable intensification, have produced extensive research bases, but do not engage or overlap with each other. This analysis examines how these ‘silos’ may hamper further research.

Klara Fischer
Giulia Vico
Riccardo Bommarco
ResearchOpen Access02 Dec 2024
Nature Sustainability

Volume: 8, P: 66-74
High-concentration silver alloying and steep back-contact gallium grading enabling copper indium gallium selenide solar cell with 23.6% efficiency

Keller et al. use high-concentration silver alloying and steep gallium grading close to the back contact to minimize bandgap fluctuations and thus voltage losses, achieving 23.6% certified efficiency in Cu(In,Ga)Se₂ solar cells.

Jan Keller
Klara Kiselman
Marika Edoff
ResearchOpen Access19 Feb 2024
Nature Energy

Volume: 9, P: 467-478
Delayed generation of functional virus-specific circulating T follicular helper cells correlates with severe COVID-19

T follicular helper cells (Tfh) enhance antibody responses and can circulate or be resident in lymph nodes. Here the authors show that during acute SARS-CoV-2 infection, circulating Tfh cells correlate with antibody titres and plasmablast levels but in more severe COVID-19 cases, cTfh generation is delayed.

Meng Yu
Afandi Charles
Anna Smed-Sörensen
ResearchOpen Access15 Apr 2023
Nature Communications

Volume: 14, P: 1-14
DNMT3A clonal hematopoiesis-driver mutations induce cardiac fibrosis by paracrine activation of fibroblasts

This study uncovers a critical link between DNMT3A-driven CHIP and heart failure and, in particular, it shows that DNMT3A inactivation in monocytes boosts the release of HB-EGF, which activates fibroblasts inducing diffuse fibrosis in the heart.

Mariana Shumliakivska
Guillermo Luxán
Stefanie Dimmeler
ResearchOpen Access19 Jan 2024
Nature Communications

Volume: 15, P: 1-20
Photoswitchable paclitaxel-based microtubule stabilisers allow optical control over the microtubule cytoskeleton

Light-based modulation of the microtubule (MT) cytoskeleton is an attractive goal for spatiotemporally-resolved MT studies. Here the authors develop a first generation photoswitchable small molecule MT stabiliser based on paclitaxel, allowing optical control over cellular MT dynamics.

Adrian Müller-Deku
Joyce C. M. Meiring
Oliver Thorn-Seshold
ResearchOpen Access15 Sept 2020
Nature Communications

Volume: 11, P: 1-12
Co-regulation of the transcription controlling ATF2 phosphoswitch by JNK and p38

The ATF2 transcription factor is phosphorylated by different mitogen-activated protein (MAP) kinases. Here, the authors show that the functionally distinct MAP kinases JNK and p38 control ATF2 through different binding sites and differential phosphorylation, thereby modulating ATF2’s sensitivity to the JNK and p38 pathways.

Klára Kirsch
András Zeke
Attila Reményi
ResearchOpen Access13 Nov 2020
Nature Communications

Volume: 11, P: 1-15
The scientific narrative around new food technologies needs to change

The scientific narrative around food biotechnologies, such as genetically modified crops, is ineffective at predicting their role in the development and change of agricultural practices and food. Here, we suggest placing the scientific discussion of new food technologies in the context of the political and economic forces that shape agriculture.

Klara Fischer
Joeva Sean Rock
Comments & Opinion04 Oct 2023
Nature Reviews Bioengineering

Volume: 1, P: 786-787
A translational protocol optimizes the isolation of plasma-derived extracellular vesicle proteomics

Jussara Ríos de los Ríos Reséndiz
Freya Herrmann-Sim
Katharina Clemm von Hohenberg
ResearchOpen Access07 Jul 2025
Scientific Reports

Volume: 15, P: 1-17
Tumor-derived GDF-15 blocks LFA-1 dependent T cell recruitment and suppresses responses to anti-PD-1 treatment

Here authors show that GDF15, a cytokine that is produced by cancer cells, prevents T cells from extravasation into the tumour microenvironment. Low availability of T cells in GDF-15-expressing tumours thus precludes effective immune therapy.

Markus Haake
Beatrice Haack
Jörg Wischhusen
ResearchOpen Access20 Jul 2023
Nature Communications

Volume: 14, P: 1-19
Combined nanopore and single-molecule real-time sequencing survey of human betaherpesvirus 5 transcriptome

Balázs Kakuk
Dóra Tombácz
Zsolt Boldogkői
ResearchOpen Access14 Jul 2021
Scientific Reports

Volume: 11, P: 1-14
Primary tumour location, molecular alterations, treatments, and outcome in a population-based metastatic colorectal cancer cohort

Emerik Osterlund
Klara Hammarström
Bengt Glimelius
ResearchOpen Access28 May 2025
BJC Reports

Volume: 3, P: 1-14
Lasing in Live Mitotic and Non-Phagocytic Cells by Efficient Delivery of Microresonators

Marcel Schubert
Klara Volckaert
Malte C. Gather
ResearchOpen Access19 Jan 2017
Scientific Reports

Volume: 7, P: 1-9
Phosphorylation of S122 in ERα is important for the skeletal response to estrogen treatment in male mice

Karin Horkeby
Helen H. Farman
Marie K. Lagerquist
ResearchOpen Access27 Dec 2022
Scientific Reports

Volume: 12, P: 1-10
Overexpression of the WAPO-A1 gene increases the number of spikelets per spike in bread wheat

Lukas M. Wittern
Jose M. Barrero
Matthew A. Hannah
ResearchOpen Access20 Aug 2022
Scientific Reports

Volume: 12, P: 1-15
High miR-451 expression in peripheral blood mononuclear cells from subjects at risk of developing rheumatoid arthritis

Klára Prajzlerová
Olga Kryštůfková
Mária Filková
ResearchOpen Access25 Feb 2021
Scientific Reports

Volume: 11, P: 1-9
Perinatal stress and human hippocampal volume: Findings from typically developing young adults

Klára Marečková
Radek Mareček
Milan Brázdil
ResearchOpen Access16 Mar 2018
Scientific Reports

Volume: 8, P: 1-10
Pollen-mediated gene flow and seed exchange in small-scale Zambian maize farming, implications for biosafety assessment

Thomas Bøhn
Denis W. Aheto
Broder Breckling
ResearchOpen Access03 Oct 2016
Scientific Reports

Volume: 6, P: 1-12

Search

Milestone in predicting core plasma turbulence: successful multi-channel validation of the gyrokinetic code GENE

Real-world analysis of immune checkpoint inhibitor efficacy and response predictors in patients treated at the CCCMunich^LMU outpatient clinic

Simultaneous targeting of KRAS and CDK4 synergistically induces durable growth arrest in pancreatic cancer cells

The hypolipidemic effect of MI-883, the combined CAR agonist/ PXR antagonist, in diet-induced hypercholesterolemia model

An LKB1–mitochondria axis controls T_H17 effector function

Progress towards sustainable agriculture hampered by siloed scientific discourses

High-concentration silver alloying and steep back-contact gallium grading enabling copper indium gallium selenide solar cell with 23.6% efficiency

Delayed generation of functional virus-specific circulating T follicular helper cells correlates with severe COVID-19

DNMT3A clonal hematopoiesis-driver mutations induce cardiac fibrosis by paracrine activation of fibroblasts

Photoswitchable paclitaxel-based microtubule stabilisers allow optical control over the microtubule cytoskeleton

Co-regulation of the transcription controlling ATF2 phosphoswitch by JNK and p38

The scientific narrative around new food technologies needs to change

A translational protocol optimizes the isolation of plasma-derived extracellular vesicle proteomics

Tumor-derived GDF-15 blocks LFA-1 dependent T cell recruitment and suppresses responses to anti-PD-1 treatment

Combined nanopore and single-molecule real-time sequencing survey of human betaherpesvirus 5 transcriptome

Primary tumour location, molecular alterations, treatments, and outcome in a population-based metastatic colorectal cancer cohort

Lasing in Live Mitotic and Non-Phagocytic Cells by Efficient Delivery of Microresonators

Phosphorylation of S122 in ERα is important for the skeletal response to estrogen treatment in male mice

Overexpression of the WAPO-A1 gene increases the number of spikelets per spike in bread wheat

High miR-451 expression in peripheral blood mononuclear cells from subjects at risk of developing rheumatoid arthritis

Perinatal stress and human hippocampal volume: Findings from typically developing young adults

Pollen-mediated gene flow and seed exchange in small-scale Zambian maize farming, implications for biosafety assessment

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