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Advanced filters: Author: Klaus-Peter Janßen Clear advanced filters

Universal, untargeted detection of bacteria in tissues using metabolomics workflows

In this study, authors introduce small molecular taxon-specific markers for bacterial detection directly in complex matrices using MS-based (spatial) metabolomics. This method has the potential to advance microbiological diagnostics and host-microbe research.

Wei Chen
Min Qiu
Nicole Strittmatter
ResearchOpen Access02 Jan 2025
Nature Communications

Volume: 16, P: 1-12
Bacillamide D produced by Bacillus cereus from the mouse intestinal bacterial collection (miBC) is a potent cytotoxin in vitro

A biosynthetic gene cluster from a Bacillus strain from the mouse gut produces bacillamide D, a selective cytotoxin, inhibiting growth and motility of human cell lines and murine organoids in vitro.

Maximilian Hohmann
Valentina Brunner
Tobias A. M. Gulder
ResearchOpen Access28 May 2024
Communications Biology

Volume: 7, P: 1-11

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Universal, untargeted detection of bacteria in tissues using metabolomics workflows

Bacillamide D produced by Bacillus cereus from the mouse intestinal bacterial collection (miBC) is a potent cytotoxin in vitro

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