GABA depolarizes immature neurons in the central nervous system, yet the mode of GABA action in the developing brain is unknown. Here the authors demonstrate thatin vivoGABA acts as a depolarizing neurotransmitter imposing inhibitory control on network activity in the mouse postnatal day 3–4 neocortex.
- Knut Kirmse
- Michael Kummer
- Knut Holthoff
