Nucleophilic addition reactions of propargyl cations can result in diverse synthetically useful compounds, however, dehydrative propargylation through α-alkyl-propargyl cations remains challenging. Here, the authors utilize a highly oxophilic indium cation to generate α-alkyl-propargyl cations from secondary alcohols and apply them to SN1-propargylation.
- Mitsuhiro Yoshimatsu
- Hiroki Goto
- Yoshiharu Sawada
