This study reports Stomidazolone, a doubly-sulfonylated imidazolone that inhibits stomatal differentiation by binding to the ACT-Like domain of MUTE, disrupting its interaction with the bHLH partner SCREAM, which expands the chemical toolkit for manipulating bHLH-ACTL protein interactions, offering new avenues for controlling plant development.
- Ayami Nakagawa
- Krishna Mohan Sepuru
- Keiko U. Torii